Literature DB >> 9513619

Rheumatic manifestations of scurvy. A report of two cases.

J Léone1, V Delhinger, D Maes, C Scheer, J L Pennaforte, J P Eschard, J C Etienne.   

Abstract

Bleeding into the muscles and joints can be the presenting manifestation of scurvy, as illustrated by two case-reports. One patient presented with hemarthrosis of the tibiotalar joint due to an insufficiency fracture and was suspected to have scurvy based on the presence of purpura and hypertrophy of the gums with loss of teeth. In the other patient, multiple hematomas in the lower limbs were found at presentation and the presence of coiled hairs suggested the diagnosis. Both patients had completely eliminated fruit and vegetables from their diet. Low levels of ascorbic acid were found in serum and urine. A full recovery was achieved in both cases under ascorbic acid supplementation.

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Year:  1997        PMID: 9513619

Source DB:  PubMed          Journal:  Rev Rhum Engl Ed        ISSN: 1169-8446


  2 in total

1.  Ascorbic acid insufficiency induces the severe defect on bone formation via the down-regulation of osteocalcin production.

Authors:  Won Kim; Seyeon Bae; Hyemin Kim; Yejin Kim; Jiwon Choi; Sun Young Lim; Hei Jin Lee; Jihyuk Lee; Jiyea Choi; Mirim Jang; Kyoung Eun Lee; Sun G Chung; Young-Il Hwang; Jae Seung Kang; Wang Jae Lee
Journal:  Anat Cell Biol       Date:  2013-12-24

2.  A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice.

Authors:  Cheng-Wei Lai; Hsiao-Ling Chen; Min-Yu Tu; Wei-Yu Lin; Theresa Röhrig; Shang-Hsun Yang; Ying-Wei Lan; Kowit-Yu Chong; Chuan-Mu Chen
Journal:  Oncotarget       Date:  2017-01-31
  2 in total

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