Literature DB >> 9513592

(R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist.

I T Forbes1, S Dabbs, D M Duckworth, A J Jennings, F D King, P J Lovell, A M Brown, L Collin, J J Hagan, D N Middlemiss, G J Riley, D R Thomas, N Upton.   

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Year:  1998        PMID： 9513592     DOI： 10.1021/jm970519e

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  17 in total

1.  [(3)H]-SB-269970--A selective antagonist radioligand for 5-HT(7) receptors.

Authors:  D R Thomas; P J Atkinson; M Ho; S M Bromidge; P J Lovell; A J Villani; J J Hagan; D N Middlemiss; G W Price
Journal:  Br J Pharmacol       Date:  2000-05       Impact factor: 8.739

Review 2.  Serotonin 5-HT7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disorders.

Authors:  Marcello Leopoldo; Enza Lacivita; Francesco Berardi; Roberto Perrone; Peter B Hedlund
Journal:  Pharmacol Ther       Date:  2010-10-20       Impact factor: 12.310

3.  Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

Authors:  J J Hagan; G W Price; P Jeffrey; N J Deeks; T Stean; D Piper; M I Smith; N Upton; A D Medhurst; D N Middlemiss; G J Riley; P J Lovell; S M Bromidge; D R Thomas
Journal:  Br J Pharmacol       Date:  2000-06       Impact factor: 8.739

4.  5-CT stimulation of adenylyl cyclase activity in guinea-pig hippocampus: evidence for involvement of 5-HT7 and 5-HT1A receptors.

Authors:  D R Thomas; D N Middlemiss; S G Taylor; P Nelson; A M Brown
Journal:  Br J Pharmacol       Date:  1999-09       Impact factor: 8.739

5.  Luminal 5-HT stimulates colonic bicarbonate secretion in rats.

Authors:  I Kaji; Y Akiba; H Said; K Narimatsu; J D Kaunitz
Journal:  Br J Pharmacol       Date:  2015-08-26       Impact factor: 8.739

6.  5-HT6/7 receptor antagonists facilitate dopamine release in the cochlea via a GABAergic disinhibitory mechanism.

Authors:  Zoltán Doleviczényi; E Sylvester Vizi; István Gacsályi; Katalin Pallagi; Balázs Volk; László G Hársing; György Halmos; Balázs Lendvai; Tibor Zelles
Journal:  Neurochem Res       Date:  2008-07-29       Impact factor: 3.996

7.  Evidence that 5-hydroxytryptamine(7) receptors play a role in the mediation of afferent transmission within the nucleus tractus solitarius in anaesthetized rats.

Authors:  Diana Oskutyte; David Jordan; Andrew G Ramage
Journal:  Br J Pharmacol       Date:  2009-09-28       Impact factor: 8.739

8.  A 5-HT7 heteroreceptor-mediated inhibition of [3H]serotonin release in raphe nuclei slices of the rat: evidence for a serotonergic-glutamatergic interaction.

Authors:  Laszlo G Harsing; Ibolya Prauda; Jozsef Barkoczy; Peter Matyus; Zsolt Juranyi
Journal:  Neurochem Res       Date:  2004-08       Impact factor: 3.996

9.  The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat.

Authors:  L G Harsing
Journal:  Curr Neuropharmacol       Date:  2006-10       Impact factor: 7.363

10.  No hypothermic response to serotonin in 5-HT7 receptor knockout mice.

Authors:  P B Hedlund; P E Danielson; E A Thomas; K Slanina; M J Carson; J G Sutcliffe
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-15       Impact factor: 11.205
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