Literature DB >> 9512412

Epstein-Barr virus: LMP1 masquerades as an active receptor.

A G Eliopoulos1, A B Rickinson.   

Abstract

The Epstein-Barr virus protein LMP1 is essential for transformation of resting B cells by the virus, but how it works is unclear. Recent results suggest that LMP1 acts as a constitutively active receptor that shares certain characteristics with members of the tumour necrosis factor receptor superfamily.

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Year:  1998        PMID: 9512412     DOI: 10.1016/s0960-9822(98)70123-x

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  16 in total

1.  Preferential localization of the Epstein-Barr virus (EBV) oncoprotein LMP-1 to nuclei in human T cells: implications for its role in the development of EBV genome-positive T-cell lymphomas.

Authors:  Jingwu Xu; Ali Ahmad; José Menezes
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

2.  Transmembrane domains 1 and 2 of the latent membrane protein 1 of Epstein-Barr virus contain a lipid raft targeting signal and play a critical role in cytostasis.

Authors:  William F Coffin; Timothy R Geiger; Jennifer M Martin
Journal:  J Virol       Date:  2003-03       Impact factor: 5.103

3.  Latent membrane protein 1 deletion mutants accumulate in reed-sternberg cells of human immunodeficiency virus-related Hodgkin's lymphoma.

Authors:  Massimo Guidoboni; Maurilio Ponzoni; Laura Caggiari; Antonia A Lettini; Luca Vago; Valli De Re; Annunziata Gloghini; Paola Zancai; Antonino Carbone; Mauro Boiocchi; Riccardo Dolcetti
Journal:  J Virol       Date:  2005-02       Impact factor: 5.103

4.  A membrane leucine heptad contributes to trafficking, signaling, and transformation by latent membrane protein 1.

Authors:  Jisook Lee; Bill Sugden
Journal:  J Virol       Date:  2007-06-20       Impact factor: 5.103

5.  Unique signaling properties of CTAR1 in LMP1-mediated transformation.

Authors:  Bernardo A Mainou; David N Everly; Nancy Raab-Traub
Journal:  J Virol       Date:  2007-07-11       Impact factor: 5.103

6.  Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha.

Authors:  R Weil; H Sirma; C Giannini; D Kremsdorf; C Bessia; C Dargemont; C Bréchot; A Israël
Journal:  Mol Cell Biol       Date:  1999-09       Impact factor: 4.272

7.  PRA1 promotes the intracellular trafficking and NF-kappaB signaling of EBV latent membrane protein 1.

Authors:  Hao-Ping Liu; Chih-Ching Wu; Yu-Sun Chang
Journal:  EMBO J       Date:  2006-08-17       Impact factor: 11.598

8.  Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins.

Authors:  O Gires; F Kohlhuber; E Kilger; M Baumann; A Kieser; C Kaiser; R Zeidler; B Scheffer; M Ueffing; W Hammerschmidt
Journal:  EMBO J       Date:  1999-06-01       Impact factor: 11.598

9.  Epstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2.

Authors:  A G Eliopoulos; S M Blake; J E Floettmann; M Rowe; L S Young
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

10.  Human monocytic cell lines transformed in vitro by Epstein-Barr virus display a type II latency and LMP-1-dependent proliferation.

Authors:  Eric Masy; Eric Adriaenssens; Claire Montpellier; Pascale Crépieux; Alexandra Mougel; Brigitte Quatannens; Gautier Goormachtigh; Nathalie Faumont; Fabienne Meggetto; Claude Auriault; Hervé Groux; Jean Coll
Journal:  J Virol       Date:  2002-07       Impact factor: 5.103

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