| Literature DB >> 951142 |
G J Schwartz, G B Haycock, C M Edelmann, A Spitzer.
Abstract
Based on statistical analysis of data in 186 children, a formula was derived which allows accurate estimation of glomerular filtration rate (GFR) from plasma creatinine and body lenght (GFR(ml/min/1.73 sq m) = 0.55 length (cm)/Per (mg/dl). Its application to clearance data in a separate group of 223 children reveals excellent agreement with GFR estimated by the Ccr (r = .935) or Cin (r = .905). This formula should be useful for adjusting dosages of drugs excreted by the kidney and detecting significant changes in renal function.Entities:
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Year: 1976 PMID： 951142
Source DB: PubMed Journal: Pediatrics ISSN： 0031-4005 Impact factor: 7.124