Literature DB >> 9508759

Agonist efficacy and allosteric models of receptor action.

H O Onaran1, T Costa.   

Abstract

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Year:  1997        PMID： 9508759     DOI： 10.1111/j.1749-6632.1997.tb48150.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


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  16 in total

1.  Constitutively active mutants of 5-HT4 receptors are they in unique active states?

Authors:  S Claeysen; M Sebben; C Bécamel; M L Parmentier; A Dumuis; J Bockaert
Journal:  EMBO Rep       Date:  2001-01       Impact factor: 8.807

Review 2.  Biased signalling and allosteric machines: new vistas and challenges for drug discovery.

Authors:  Terry P Kenakin
Journal:  Br J Pharmacol       Date:  2012-03       Impact factor: 8.739

Review 3.  Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.

Authors:  Terry Kenakin; Laurence J Miller
Journal:  Pharmacol Rev       Date:  2010-04-14       Impact factor: 25.468

Review 4.  The mass action equation in pharmacology.

Authors:  Terry Kenakin
Journal:  Br J Clin Pharmacol       Date:  2015-12-21       Impact factor: 4.335

Review 5.  Pharmacological onomastics: what's in a name?

Authors:  T P Kenakin
Journal:  Br J Pharmacol       Date:  2007-08-13       Impact factor: 8.739

Review 6.  Cellular assays as portals to seven-transmembrane receptor-based drug discovery.

Authors:  Terry P Kenakin
Journal:  Nat Rev Drug Discov       Date:  2009-07-17       Impact factor: 84.694

Review 7.  Gaddum Memorial Lecture 2014: receptors as an evolving concept: from switches to biased microprocessors.

Authors:  Terry Kenakin
Journal:  Br J Pharmacol       Date:  2015-07-21       Impact factor: 8.739

Review 8.  New concepts in pharmacological efficacy at 7TM receptors: IUPHAR review 2.

Authors:  Terry Kenakin
Journal:  Br J Pharmacol       Date:  2013-02       Impact factor: 8.739

9.  Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor.

Authors:  Andreas Bock; Marcel Bermudez; Fabian Krebs; Carlo Matera; Brian Chirinda; Dominique Sydow; Clelia Dallanoce; Ulrike Holzgrabe; Marco De Amici; Martin J Lohse; Gerhard Wolber; Klaus Mohr
Journal:  J Biol Chem       Date:  2016-06-13       Impact factor: 5.157

10.  Allosteric theory: taking therapeutic advantage of the malleable nature of GPCRs.

Authors:  Terry Kenakin
Journal:  Curr Neuropharmacol       Date:  2007-09       Impact factor: 7.363
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