Literature DB >> 9506655

Eight-epi-PGF2alpha: a possible marker of lipid peroxidation in term infants with severe pulmonary disease.

S Goil1, W E Truog, C Barnes, M Norberg, M Rezaiekhaligh, D Thibeault.   

Abstract

A prostaglandin F2-like compound, 8-epi-PGF2alpha, formed from oxidation of arachidonate, has been proposed as an indicator of lipid peroxidation. We determined whether tracheal aspirate or urinary 8-epi-PGF2alpha levels would differ over time or between infants in a control group and infants with severe respiratory failure. We correlated tracheal aspirate 8-epi-PGF2alpha levels with the fraction of inspired oxygen and with mean airway pressures at 24 and 48 hours of life. Levels in tracheal aspirates were in the range of 0 to 36 pg/microg of fSC of IgA and were higher in infants with severe pulmonary disorders compared with those in infants in the control group (p < 0.02). Urinary concentrations did not discriminate between sick infants and infants in the control group.

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Year:  1998        PMID： 9506655     DOI： 10.1016/s0022-3476(98)70459-7

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  7 in total

1.  Pulmonary arterial contractility in neonatal lambs increases with 100% oxygen resuscitation.

Authors:  Satyan Lakshminrusimha; James A Russell; Robin H Steinhorn; Rita M Ryan; Sylvia F Gugino; Frederick C Morin; Daniel D Swartz; Vasanth H Kumar
Journal:  Pediatr Res       Date:  2005-12-02       Impact factor: 3.756

2.  Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene.

Authors:  Vijay S Thakur; Yanhong W Liang; Krithika Lingappan; Weiwu Jiang; Lihua Wang; Roberto Barrios; Guodong Zhou; Bharath Guntupalli; Binoy Shivanna; Paramahamsa Maturu; Stephen E Welty; Bhagavatula Moorthy; Xanthi I Couroucli
Journal:  Toxicol Lett       Date:  2014-03-19       Impact factor: 4.372

3.  Safety and efficacy of nitric oxide in chronic lung disease.

Authors:  P L Clark; I I Ekekezie; H A Kaftan; C A Castor; W E Truog
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2002-01       Impact factor: 5.747

4.  Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants.

Authors:  Xanthi I Couroucli; Yan-hong Wei Liang; Weiwu Jiang; Lihua Wang; Roberto Barrios; Peiying Yang; Bhagavatula Moorthy
Journal:  Toxicol Appl Pharmacol       Date:  2011-06-26       Impact factor: 4.219

5.  Superoxide dismutase improves oxygenation and reduces oxidation in neonatal pulmonary hypertension.

Authors:  Satyan Lakshminrusimha; James A Russell; Stephen Wedgwood; Sylvia F Gugino; Jeffrey A Kazzaz; Jonathan M Davis; Robin H Steinhorn
Journal:  Am J Respir Crit Care Med       Date:  2006-09-28       Impact factor: 21.405

6.  Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal β-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants.

Authors:  Paramahamsa Maturu; Yanhong Wei-Liang; Weiwu Jiang; Lihua Wang; Krithika Lingappan; Roberto Barrios; Yao Liang; Bhagavatula Moorthy; Xanthi I Couroucli
Journal:  Toxicol Sci       Date:  2017-05-01       Impact factor: 4.849

Review 7.  Oxygen, gastrin-releasing Peptide, and pediatric lung disease: life in the balance.

Authors:  Mary E Sunday
Journal:  Front Pediatr       Date:  2014-07-18       Impact factor: 3.418
  7 in total

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