Literature DB >> 9504

Isolation and characterization of the cardiotonic polypeptide anthopleurin-A from the sea anemone Anthopleura xanthogrammica.

T R Norton, S Shibata, M Kashiwagi, J Bentley.   

Abstract

A highly potent cardiotonic polypeptide, anthopleurin-A, was isolated from the sea anemone, Anthopleura xanthogrammica (Brandt), using solvent partition, gel permeation chromatography, and cation-exchange chromatography. It is a pure basic polypeptide wtih a molecular weight of about 5500.

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Year:  1976        PMID： 9504     DOI： 10.1002/jps.2600650927

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  7 in total

Review 1.  Site-3 toxins and cardiac sodium channels.

Authors:  Dorothy A Hanck; Michael F Sheets
Journal:  Toxicon       Date:  2006-09-27       Impact factor: 3.033

2.  Polypeptide neurotoxins modify gating and apparent single-channel conductance of veratridine-activated sodium channels in planar lipid bilayers.

Authors:  A M Corbett; B K Krueger
Journal:  J Membr Biol       Date:  1989-09       Impact factor: 1.843

3.  Possible mechanism of the dual action of the new polypeptide (anthopleurin-B) from sea anemone in the isolated ileum and taenia caeci of the guinea-pig.

Authors:  Y Ohizumi; S Shibata
Journal:  Br J Pharmacol       Date:  1981-02       Impact factor: 8.739

4.  Excitatory effect of a new polypeptide (anthopleurin-B) from sea anemone on the guinea-pig vas deferens.

Authors:  T R Norton; Y Ohizumi; S Shibata
Journal:  Br J Pharmacol       Date:  1981-09       Impact factor: 8.739

5.  Electromechanical effects of anthopleurin-A (AP-A) on rabbit ventricular muscle: influence of driving frequency, calcium antagonists, tetrodotoxin, lidocaine and ryanodine.

Authors:  I Kodama; S Shibata; J Toyama; K Yamada
Journal:  Br J Pharmacol       Date:  1981-09       Impact factor: 8.739

Review 6.  Marine Peptides: Bioactivities and Applications.

Authors:  Randy Chi Fai Cheung; Tzi Bun Ng; Jack Ho Wong
Journal:  Mar Drugs       Date:  2015-06-29       Impact factor: 5.118

Review 7.  Voltage-Gated Sodium Channels: A Prominent Target of Marine Toxins.

Authors:  Rawan Mackieh; Rita Abou-Nader; Rim Wehbe; César Mattei; Christian Legros; Ziad Fajloun; Jean Marc Sabatier
Journal:  Mar Drugs       Date:  2021-10-05       Impact factor: 5.118
  7 in total

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