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Literature DB >> 9503262

Calcium homeostasis in ageing: studies on the calcium binding protein calbindin D28K.

G Lally¹, R L Faull, H J Waldvogel, S Ferrari, P C Emson.

Abstract

Calbindin D28K is a neuronal calcium binding protein which may act as a buffer of neuronal calcium. Evidence suggests that disturbance of calcium homeostasis is important in neurodegeneration, possibly via changes in calbindin D28K. Immunoreactivity of calbindin D28K is compared in Alzheimer's disease and age-matched controls. The size and number of calbindin D28K positive neurons in Alzheimer's disease tissue is reduced. There is also shrinkage of the dendritic tree. Continuing work examines the function of calbindin D28K using transgenic mice.

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Year: 1997 PMID： 9503262 DOI： 10.1007/BF01273323

Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.575

11 in total

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Authors: P R Hof; J H Morrison
Journal: Exp Neurol Date: 1991-03 Impact factor: 5.330

2. Developmental and age-dependent changes of 28-kDa calbindin-D in the central nervous tissue determined with a sensitive immunoassay method.

Authors: N Kurobe; Y Inaguma; H Shinohara; R Semba; T Inagaki; K Kato
Journal: J Neurochem Date: 1992-01 Impact factor: 5.372

3. Immunohistochemical localization of the somatostatin SST2(A) receptor in the rat brain and spinal cord.

Authors: M Schindler; L A Sellers; P P Humphrey; P C Emson
Journal: Neuroscience Date: 1997-01 Impact factor: 3.590

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Authors: A P Davenport; S J Augood; D E Lawson; P C Emson
Journal: Cell Mol Biol Date: 1990 Impact factor: 1.770

5. Calbindin-immunoreactive cholinergic neurones in the nucleus basalis of Meynert in Alzheimer-type dementia.

Authors: Y Ichimiya; P C Emson; C Q Mountjoy; D E Lawson; R Iizuka
Journal: Brain Res Date: 1989-10-16 Impact factor: 3.252

6. Vitamin d3-induced calcium-binding protein in chick intestinal mucosa.

Authors: R H Wasserman; A N Taylor
Journal: Science Date: 1966-05-06 Impact factor: 47.728

Review 7. Calcium signaling in neurons: molecular mechanisms and cellular consequences.

Authors: A Ghosh; M E Greenberg
Journal: Science Date: 1995-04-14 Impact factor: 47.728

8. Stable transfection of calbindin-D28k into the GH3 cell line alters calcium currents and intracellular calcium homeostasis.

Authors: P M Lledo; B Somasundaram; A J Morton; P C Emson; W T Mason
Journal: Neuron Date: 1992-11 Impact factor: 17.173

9. Loss of calbindin-28K immunoreactive neurones from the cortex in Alzheimer-type dementia.

Authors: Y Ichimiya; P C Emson; C Q Mountjoy; D E Lawson; C W Heizmann
Journal: Brain Res Date: 1988-12-13 Impact factor: 3.252

10. Deficits in memory and hippocampal long-term potentiation in mice with reduced calbindin D28K expression.

Authors: S Molinari; R Battini; S Ferrari; L Pozzi; A S Killcross; T W Robbins; A Jouvenceau; J M Billard; P Dutar; Y Lamour; W A Baker; H Cox; P C Emson
Journal: Proc Natl Acad Sci U S A Date: 1996-07-23 Impact factor: 11.205

5 in total

Review 1. Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome.

Authors: Eric D Hamlett; Heather A Boger; Aurélie Ledreux; Christy M Kelley; Elliott J Mufson; Maria F Falangola; David N Guilfoyle; Ralph A Nixon; David Patterson; Nathan Duval; Ann-Charlotte E Granholm
Journal: Curr Alzheimer Res Date: 2016 Impact factor: 3.498