Literature DB >> 9502314

Protein aggregation: folding aggregates, inclusion bodies and amyloid.

A L Fink1.   

Abstract

Aggregation results in the formation of inclusion bodies, amyloid fibrils and folding aggregates. Substantial data support the hypothesis that partially folded intermediates are key precursors to aggregates, that aggregation involves specific intermolecular interactions and that most aggregates involve beta sheets.

Mesh：

Substances：

Year:  1998        PMID： 9502314     DOI： 10.1016/S1359-0278(98)00002-9

Source DB:  PubMed          Journal:  Fold Des        ISSN： 1359-0278


  254 in total

1.  Atmospheric aerosols as prebiotic chemical reactors.

Authors:  C M Dobson; G B Ellison; A F Tuck; V Vaida
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

2.  Specificity in intracellular protein aggregation and inclusion body formation.

Authors:  R S Rajan; M E Illing; N F Bence; R R Kopito
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-30       Impact factor: 11.205

3.  Conformational characterization of oligomeric intermediates and aggregates in beta-lactoglobulin heat aggregation.

Authors:  R Carrotta; R Bauer; R Waninge; C Rischel
Journal:  Protein Sci       Date:  2001-07       Impact factor: 6.725

4.  Multistep nucleus formation and a separate subunit contribution of the amyloidgenesis of heat-denatured monellin.

Authors:  T Konno
Journal:  Protein Sci       Date:  2001-10       Impact factor: 6.725

5.  Hierarchical self-assembly of chiral rod-like molecules as a model for peptide beta -sheet tapes, ribbons, fibrils, and fibers.

Authors:  A Aggeli; I A Nyrkova; M Bell; R Harding; L Carrick; T C McLeish; A N Semenov; N Boden
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-09       Impact factor: 11.205

6.  Three-dimensional domain swapping in p13suc1 occurs in the unfolded state and is controlled by conserved proline residues.

Authors:  F Rousseau; J W Schymkowitz; H R Wilkinson; L S Itzhaki
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-08       Impact factor: 11.205

7.  Inverse relationship of protein concentration and aggregation.

Authors:  Michael J Treuheit; Andrew A Kosky; David N Brems
Journal:  Pharm Res       Date:  2002-04       Impact factor: 4.200

8.  Exploring protein aggregation and self-propagation using lattice models: phase diagram and kinetics.

Authors:  R I Dima; D Thirumalai
Journal:  Protein Sci       Date:  2002-05       Impact factor: 6.725

9.  High pressure fosters protein refolding from aggregates at high concentrations.

Authors:  R J St John; J F Carpenter; T W Randolph
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-09       Impact factor: 11.205

10.  Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor.

Authors:  Eva Y Chi; Sampathkumar Krishnan; Brent S Kendrick; Byeong S Chang; John F Carpenter; Theodore W Randolph
Journal:  Protein Sci       Date:  2003-05       Impact factor: 6.725
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