Literature DB >> 9501913

Conformational adaptation of agonists to the human nuclear receptor RAR gamma.

B P Klaholz1, J P Renaud, A Mitschler, C Zusi, P Chambon, H Gronemeyer, D Moras.   

Abstract

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Year:  1998        PMID： 9501913     DOI： 10.1038/nsb0398-199

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN： 1072-8368


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  29 in total

1.  Rational discovery of novel nuclear hormone receptor antagonists.

Authors:  M Schapira; B M Raaka; H H Samuels; R Abagyan
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-01       Impact factor: 11.205

2.  Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma.

Authors:  B P Klaholz; A Mitschler; M Belema; C Zusi; D Moras
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

3.  A genetic algorithm for the automated generation of small organic molecules: drug design using an evolutionary algorithm.

Authors:  D Douguet; E Thoreau; G Grassy
Journal:  J Comput Aided Mol Des       Date:  2000-07       Impact factor: 3.686

4.  Mass-spectrometric analysis of agonist-induced retinoic acid receptor gamma conformational change.

Authors:  Valerie J Peterson; Elisabeth Barofsky; Max L Deinzer; Marcia I Dawson; Kai-Chia Feng; Xiao-kun Zhang; Machender R Madduru; Mark Leid
Journal:  Biochem J       Date:  2002-02-15       Impact factor: 3.857

5.  Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.

Authors:  G Tocchini-Valentini; N Rochel; J M Wurtz; A Mitschler; D Moras
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-08       Impact factor: 11.205

6.  Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid.

Authors:  P F Egea; A Mitschler; N Rochel; M Ruff; P Chambon; D Moras
Journal:  EMBO J       Date:  2000-06-01       Impact factor: 11.598

Review 7.  Selective estrogen receptor modulators.

Authors:  Henry U Bryant
Journal:  Rev Endocr Metab Disord       Date:  2002-09       Impact factor: 6.514

8.  Folding and stability of the ligand-binding domain of the glucocorticoid receptor.

Authors:  Stephen H McLaughlin; Sophie E Jackson
Journal:  Protein Sci       Date:  2002-08       Impact factor: 6.725

9.  Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation.

Authors:  Stefan Svensson; Tove Ostberg; Micael Jacobsson; Carina Norström; Karin Stefansson; Dan Hallén; Isabel Climent Johansson; Kristina Zachrisson; Derek Ogg; Lena Jendeberg
Journal:  EMBO J       Date:  2003-09-15       Impact factor: 11.598

10.  Antagonism in the human mineralocorticoid receptor.

Authors:  J Fagart; J M Wurtz; A Souque; C Hellal-Levy; D Moras; M E Rafestin-Oblin
Journal:  EMBO J       Date:  1998-06-15       Impact factor: 11.598
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