Literature DB >> 9499604

Demographic study of port wine stain patients attending a laser clinic: family history, prevalence of naevus anaemicus and results of prior treatment.

C M Mills1, S W Lanigan, J Hughes, A V Anstey.   

Abstract

All patients with port wine stains (PWS) attending a tunable dye laser clinic were examined by one author (SWL), forming a large group which has allowed study of the demographic data of such patients. Two hundred and eighty-three patients, 217 females (median age 24 years, range 0.5-73) and 66 males (median age 20 years, range 0.75-72), were examined. The PWS were on the face in 226, neck in 69, trunk in 36, upper limb in 35 and lower limb in 29. The commonest lesional colour was purple (63 patients), while 39 naevi were pink/red, 35 pink/ purple and 35 pink. The naevus was flat in 255 patients, cobblestoned in 28, associated with hypertrophy in 31 and with scarring in 22. Seventy-two patients (25.4%) had a positive family history of birthmarks, 20 strawberry haemangiomas and 22 PWS, the family history of PWS being higher than expected for the prevalence of this naevus in the population. One hundred and forty-six patients were also examined for naevus anaemicus which was noted in 12 (8.2%), confirming an association between these two naevi. Ninety-four patients had received previous treatment, most commonly with the argon laser (56 patients), of whom only five reported a good result, and 17 of 22 patients with treatment-related scarring had been treated with this laser. Cosmetic camouflage was used in 109 (38.5%) of patients, who usually had PWS on the face (94%), of whom only 46 (16%) had received advice of its use.

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Year:  1997        PMID: 9499604

Source DB:  PubMed          Journal:  Clin Exp Dermatol        ISSN: 0307-6938            Impact factor:   3.470


  6 in total

1.  Somatic GNAQ R183Q mutation is located within the sclera and episclera in patients with Sturge-Weber syndrome.

Authors:  Yue Wu; Cheng Peng; Lulu Huang; Hao Sun; Wenyi Guo; Li Xu; Xuming Ding; Yixin Liu; Changjuan Zeng
Journal:  Br J Ophthalmol       Date:  2021-03-11       Impact factor: 5.908

2.  Heredity of port-wine stains: investigation of families without a RASA1 mutation.

Authors:  Agneta Troilius Rubin; Edgar Lauritzen; Bo Ljunggren; Nicole Revencu; Mikka Vikkula; Åke Svensson
Journal:  J Cosmet Laser Ther       Date:  2015-03-12       Impact factor: 2.247

3.  Activation of PKCα and PI3K Kinases in Hypertrophic and Nodular Port Wine Stain Lesions.

Authors:  Rong Yin; Lin Gao; Wenbin Tan; Wei Guo; Tao Zhao; Jhon Stuart Nelson; Gang Wang
Journal:  Am J Dermatopathol       Date:  2017-10       Impact factor: 1.533

4.  Clinical outcome measures and scoring systems used in prospective studies of port wine stains: A systematic review.

Authors:  M Ingmar van Raath; Sandeep Chohan; Albert Wolkerstorfer; Chantal M A M van der Horst; Jacqueline Limpens; Xuan Huang; Baoyue Ding; Gert Storm; René R W J van der Hulst; Michal Heger
Journal:  PLoS One       Date:  2020-07-02       Impact factor: 3.240

Review 5.  The Pathogenesis of Port Wine Stain and Sturge Weber Syndrome: Complex Interactions between Genetic Alterations and Aberrant MAPK and PI3K Activation.

Authors:  Vi Nguyen; Marcelo Hochman; Martin C Mihm; J Stuart Nelson; Wenbin Tan
Journal:  Int J Mol Sci       Date:  2019-05-07       Impact factor: 5.923

Review 6.  The impact of pediatric skin disease on self-esteem.

Authors:  K L Vivar; L Kruse
Journal:  Int J Womens Dermatol       Date:  2017-12-12
  6 in total

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