| Literature DB >> 9498053 |
A P Mizisin1, G D Shelton, S Wagner, C Rusbridge, H C Powell.
Abstract
Nerve biopsy samples from two cats with spontaneously occurring diabetes were examined. The predominant nerve fiber abnormalities observed were restricted to the myelin sheath and Schwann cell. Reactive, degenerative and proliferative Schwann cell changes were evident but the most striking abnormality encountered was splitting and ballooning of the myelin sheath. These observations highlight the significance of Schwann cell injury in the pathogenesis of diabetic neuropathy.Entities:
Mesh:
Year: 1998 PMID: 9498053 DOI: 10.1007/s004010050783
Source DB: PubMed Journal: Acta Neuropathol ISSN: 0001-6322 Impact factor: 17.088