Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Tryptophan depletion in recently manic patients treated with lithium.

Literature DB >> 9494705

Tryptophan depletion in recently manic patients treated with lithium.

Abstract

BACKGROUND: Serotonin has been repeatedly implicated in the mechanism of action of lithium against acute mania. Its role, however, has never been directly confirmed.
METHODS: We studied recently manic patients successfully treated with lithium using a tryptophan depletion methodology.
RESULTS: Patients remained euthymic despite a confirmed decrease in serum tryptophan levels.
CONCLUSIONS: These data do not suggest that serotonin plays a critical role in the acute antimanic effect of lithium.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1998 PMID： 9494705 DOI： 10.1016/S0006-3223(97)00010-3

Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382

Keyword Cloud
Cited

5 in total

1. Appropriate amino acid mixtures for tryptophan depletion and tyrosine/phenylalanine depletion and the safety of long-term amino acid depletion in humans: reply.

Authors: Abdulla A-B Badawy
Journal: Psychopharmacology (Berl) Date: 2013-11-16 Impact factor: 4.530

Tryptophan depletion in recently manic patients treated with lithium.

1. Appropriate amino acid mixtures for tryptophan depletion and tyrosine/phenylalanine depletion and the safety of long-term amino acid depletion in humans: reply.

2. Total sleep time and kynurenine metabolism associated with mood symptom severity in bipolar disorder.

3. A Systematic Review of Nutraceuticals for the Treatment of Bipolar Disorder.

Review 4. Attention deficit-hyperactivity disorder and early-onset bipolar disorder: two facets of one entity?

Review 5. Nutritional therapies for mental disorders.