A Hartz1, C Guse, K Kayser, E Kuhn, D Johnson. 1. Department of Family Medicine, University of Iowa College of Medicine, Iowa City 52242-1097, USA.
Abstract
OBJECTIVE: To derive and evaluate prediction models for patients who had undergone coronary artery bypass grafting (CABG) and had a difficult postoperative course. DESIGN: Observational. SETTING: Midwestern hospital specializing in high-risk CABG procedures. PATIENTS: One hundred eighty-three patients who stayed at least 10 consecutive days in the intensive care unit after a CABG procedure. OUTCOME MEASURE: Death within 60 days of surgery. INTERVENTION: None. RESULTS: The final logistic regression prediction models included the following findings: pulmonary capillary wedge pressure, cardiac index, heart rate, urine output, positive end-expiratory pressure, blood urea nitrogen levels, and the arterial pressure of carbon dioxide. The model was able to stratify patients into four risk groups with observed 60-day mortality rates of 0.0% (n = 107), 21% (n = 39), 55% (n = 20), and 88% (n = 17). Preoperative patient information was not associated with prognosis for these patients. CONCLUSIONS: The findings suggest that a risk model that is specific for patients who have undergone CABG and is based on postoperative findings may provide useful prognostic information for patients who are having a difficult postoperative course.
OBJECTIVE: To derive and evaluate prediction models for patients who had undergone coronary artery bypass grafting (CABG) and had a difficult postoperative course. DESIGN: Observational. SETTING: Midwestern hospital specializing in high-risk CABG procedures. PATIENTS: One hundred eighty-three patients who stayed at least 10 consecutive days in the intensive care unit after a CABG procedure. OUTCOME MEASURE: Death within 60 days of surgery. INTERVENTION: None. RESULTS: The final logistic regression prediction models included the following findings: pulmonary capillary wedge pressure, cardiac index, heart rate, urine output, positive end-expiratory pressure, blood ureanitrogen levels, and the arterial pressure of carbon dioxide. The model was able to stratify patients into four risk groups with observed 60-day mortality rates of 0.0% (n = 107), 21% (n = 39), 55% (n = 20), and 88% (n = 17). Preoperative patient information was not associated with prognosis for these patients. CONCLUSIONS: The findings suggest that a risk model that is specific for patients who have undergone CABG and is based on postoperative findings may provide useful prognostic information for patients who are having a difficult postoperative course.
Authors: Judson B Williams; Eric D Peterson; Daniel Wojdyla; Ralf Harskamp; Kevin W Southerland; T Bruce Ferguson; Peter K Smith; Carmelo A Milano; Renato D Lopes Journal: J Crit Care Date: 2014-06-09 Impact factor: 3.425