Literature DB >> 9493744

Heritability of poor language achievement among twins.

J B Tomblin1, P R Buckwalter.   

Abstract

In order to examine the basis of familial associations with poor language achievement, 62 twinship pairs and 3 sets of triplets were studied in which at least one member presented poor oral language status in the absence of other developmental or sensory impairments. Rates of concordance for poor language were compared between the monozygotic (MZ) and dizygotic (DZ) pairs. Concordance for the MZ pairs was .96, whereas it was .69 for the DZ pairs. The DeFries-Fulker method for computing heritability of extreme scores was employed yielding a h2g of .45. Similar results were obtained for those pairs containing only children with performance IQs above 85, but with at least one member having language below -1 SD. A comparison of DZ twins with singleton sibling pairs with at least one affected member and of similar age showed that DZ twins were more similar with respect to language achievement than singleton pairs. Thus, twinning appeared to have influenced twin resemblance among those where at least one member presented poor language achievement. These results support the hypothesis that genetic factors contribute to the liability of poor language achievement in children who do not present other developmental or sensory disorders.

Entities:  

Mesh:

Year:  1998        PMID: 9493744     DOI: 10.1044/jslhr.4101.188

Source DB:  PubMed          Journal:  J Speech Lang Hear Res        ISSN: 1092-4388            Impact factor:   2.297


  39 in total

1.  Chromosome 7q: where autism meets language disorder?

Authors:  S E Folstein; R E Mankoski
Journal:  Am J Hum Genet       Date:  2000-07-07       Impact factor: 11.025

2.  Literacy outcomes of children with early childhood speech sound disorders: impact of endophenotypes.

Authors:  Barbara A Lewis; Allison A Avrich; Lisa A Freebairn; Amy J Hansen; Lara E Sucheston; Iris Kuo; H Gerry Taylor; Sudha K Iyengar; Catherine M Stein
Journal:  J Speech Lang Hear Res       Date:  2011-09-19       Impact factor: 2.297

3.  Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading.

Authors:  Catherine M Stein; James H Schick; H Gerry Taylor; Lawrence D Shriberg; Christopher Millard; Amy Kundtz-Kluge; Karlie Russo; Nori Minich; Amy Hansen; Lisa A Freebairn; Robert C Elston; Barbara A Lewis; Sudha K Iyengar
Journal:  Am J Hum Genet       Date:  2004-01-20       Impact factor: 11.025

4.  Highly significant linkage to the SLI1 locus in an expanded sample of individuals affected by specific language impairment.

Authors: 
Journal:  Am J Hum Genet       Date:  2004-05-03       Impact factor: 11.025

Review 5.  Genetic and environmental influences on early speech, language and literacy development.

Authors:  Marianna E Hayiou-Thomas
Journal:  J Commun Disord       Date:  2008-03-25       Impact factor: 2.288

6.  Genetic effects on children's conversational language use.

Authors:  Laura S DeThorne; Stephen A Petrill; Sara A Hart; Ron W Channell; Rebecca J Campbell; Kirby Deater-Deckard; Lee Anne Thompson; David J Vandenbergh
Journal:  J Speech Lang Hear Res       Date:  2008-04       Impact factor: 2.297

7.  Cognitive profiles and heritability estimates in the Old Order Amish.

Authors:  Ryan M Kuehner; Peter Kochunov; Katie L Nugent; Deanna E Jurius; Anya Savransky; Christopher Gaudiot; Heather A Bruce; James Gold; Alan R Shuldiner; Braxton D Mitchell; L Elliot Hong
Journal:  Psychiatr Genet       Date:  2016-08       Impact factor: 2.458

Review 8.  Defining the genetic architecture of human developmental language impairment.

Authors:  Ning Li; Christopher W Bartlett
Journal:  Life Sci       Date:  2012-02-17       Impact factor: 5.037

Review 9.  Language growth and genetics of specific language impairment.

Authors:  Mabel L Rice
Journal:  Int J Speech Lang Pathol       Date:  2013-04-25       Impact factor: 2.484

10.  Overlaps between autism and language impairment: phenomimicry or shared etiology?

Authors:  D V M Bishop
Journal:  Behav Genet       Date:  2010-07-18       Impact factor: 2.805

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.