Literature DB >> 9493262

It's not just a phase: crystallization and X-ray structure determination of bacteriorhodopsin in lipidic cubic phases.

E Gouaux1.   

Abstract

Utilization of lipidic cubic phases in the crystallization of bacteriorhodopsin (bR) has yielded long sought after crystals that diffract X-rays to 2 A resolution. The resulting structure provides new information on the protein conformation and the mechanism of proton translocation. Crystallization of bR via lipidic cubic phases may be a harbinger of new membrane protein crystallization strategies.

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Year:  1998        PMID： 9493262     DOI： 10.1016/s0969-2126(98)00002-1

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  4 in total

1.  Assembly of a polytopic membrane protein structure from the solution structures of overlapping peptide fragments of bacteriorhodopsin.

Authors:  M Katragadda; J L Alderfer; P L Yeagle
Journal:  Biophys J       Date:  2001-08       Impact factor: 4.033

2.  Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices.

Authors:  Yoav Paas; Jean Cartaud; Michel Recouvreur; Regis Grailhe; Virginie Dufresne; Eva Pebay-Peyroula; Ehud M Landau; Jean-Pierre Changeux
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-17       Impact factor: 11.205

Review 3.  The significance of G protein-coupled receptor crystallography for drug discovery.

Authors:  John A Salon; David T Lodowski; Krzysztof Palczewski
Journal:  Pharmacol Rev       Date:  2011-12       Impact factor: 25.468

4.  Pressure perturbation and differential scanning calorimetric studies of bipolar tetraether liposomes derived from the thermoacidophilic archaeon Sulfolobus acidocaldarius.

Authors:  Parkson Lee-Gau Chong; Revanur Ravindra; Monika Khurana; Verrica English; Roland Winter
Journal:  Biophys J       Date:  2005-06-24       Impact factor: 4.033
  4 in total

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