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Literature DB >> 9493126

The molecular basis of voltage-gated Ca2+ channel diversity: is it time for T?

Abstract

The existence of diversity in the voltage activated Ca2+ channel populations of vertebrate cells has been long recognized. More recently, the molecular cloning of a considerable number of Ca2+ channel subunits from cDNA libraries has indicated that the range of possible Ca2+ channel phenotypes a cell can express may be even greater than was previously appreciated. A challenge of recent years has been to resolve how the properties of recombinant channels correspond with their counterparts experimentally characterized in native cells. In this short review I will outline the properties of both native and recombinant Ca2+ channels, and will then describe the current agreements and controversies concerning their relationships to each other.

Mesh：

Substances：
Calcium Channels

Year: 1998 PMID： 9493126 DOI： 10.1007/s002329900327

Source DB: PubMed Journal: J Membr Biol ISSN： 0022-2631 Impact factor: 1.843

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Cited

10 in total

1. Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons.

Authors: Jakob Wolfart; Jochen Roeper
Journal: J Neurosci Date: 2002-05-01 Impact factor: 6.167

Review 2. Low-voltage-activated ("T-Type") calcium channels in review.

Authors: Anne Marie R Yunker; Maureen W McEnery
Journal: J Bioenerg Biomembr Date: 2003-12 Impact factor: 2.945

3. Functional properties of dopaminergic neurones in the mouse olfactory bulb.

Authors: Angela Pignatelli; Kazuto Kobayashi; Hideyuki Okano; Ottorino Belluzzi
Journal: J Physiol Date: 2005-02-24 Impact factor: 5.182

4. The neuromuscular junctions of the slow and the fast excitatory axon in the closer of the crab Eriphia spinifrons are endowed with different Ca2+ channel types and allow neuron-specific modulation of transmitter release by two neuropeptides.

Authors: Werner Rathmayer; Stjefan Djokaj; Aleksandr Gaydukov; Sabine Kreissl
Journal: J Neurosci Date: 2002-02-01 Impact factor: 6.167

5. Lambert-Eaton antibodies inhibit Ca2+ currents but paradoxically increase exocytosis during stimulus trains in bovine adrenal chromaffin cells.

Authors: K L Engisch; M M Rich; N Cook; M C Nowycky
Journal: J Neurosci Date: 1999-05-01 Impact factor: 6.167

The molecular basis of voltage-gated Ca2+ channel diversity: is it time for T?

1. Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons.

Review 2. Low-voltage-activated ("T-Type") calcium channels in review.

3. Functional properties of dopaminergic neurones in the mouse olfactory bulb.

4. The neuromuscular junctions of the slow and the fast excitatory axon in the closer of the crab Eriphia spinifrons are endowed with different Ca2+ channel types and allow neuron-specific modulation of transmitter release by two neuropeptides.

5. Lambert-Eaton antibodies inhibit Ca2+ currents but paradoxically increase exocytosis during stimulus trains in bovine adrenal chromaffin cells.

6. Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels.

7. Descending vasa recta pericytes express voltage operated Na+ conductance in the rat.

8. Effects of voltage-sensitive calcium channel blockers on extracellular dopamine levels in rat striatum.

9. Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca2+ channels via microdomain coupling.

10. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses.