Literature DB >> 9492979

Mechanisms of enhanced prevalence of asthma and atopy in developed countries.

J M Hopkin1.   

Abstract

Atopy--a T helper 2 cell driven hypersensitivity to innocuous antigens (allergens) which causes most cases of asthma-- is of complex genetic and environmental origins. There is compelling epidemiological evidence for a rise in atopic disease in 'westernised' communities. The changing pattern of microbial exposure in early childhood is suggested to be the principal candidate mechanism for this rise.

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Year:  1997        PMID： 9492979     DOI： 10.1016/s0952-7915(97)80179-3

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  12 in total

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2.  Does population mixing measure infectious exposure in children at the community level?

Authors:  John C Taylor; Graham R Law; Paul J Boyle; Zhiqiang Feng; Mark S Gilthorpe; Roger C Parslow; Gavin Rudge; Richard G Feltbower
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4.  International patterns of tuberculosis and the prevalence of symptoms of asthma, rhinitis, and eczema.

Authors:  E von Mutius; N Pearce; R Beasley; S Cheng; O von Ehrenstein; B Björkstén; S Weiland
Journal:  Thorax       Date:  2000-06       Impact factor: 9.139

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6.  Breakdown of mucosal immunity in gut by 2,3,7,8-tetraclorodibenzo-p-dioxin (TCDD).

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7.  Bifidobacterial species differentially affect expression of cell surface markers and cytokines of dendritic cells harvested from cord blood.

Authors:  Sarah L Young; Mary A Simon; Margaret A Baird; Gerald W Tannock; Rodrigo Bibiloni; Kate Spencely; Juliette M Lane; Penny Fitzharris; Julian Crane; Ian Town; Emmanuel Addo-Yobo; Clare S Murray; Ashley Woodcock
Journal:  Clin Diagn Lab Immunol       Date:  2004-07

8.  The prevalence of asthma and allergies in Singapore; data from two ISAAC surveys seven years apart.

Authors:  X S Wang; T N Tan; L P C Shek; S Y Chng; C P P Hia; N B H Ong; S Ma; B W Lee; D Y T Goh
Journal:  Arch Dis Child       Date:  2004-05       Impact factor: 3.791

9.  Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family.

Authors:  Andreas G Glaser; Andreas Limacher; Sabine Flückiger; Annika Scheynius; Leonardo Scapozza; Reto Crameri
Journal:  Biochem J       Date:  2006-05-15       Impact factor: 3.857

10.  Clinical Use of Probiotics in Pediatric Allergy (CUPPA): A World Allergy Organization Position Paper.

Authors:  Alessandro Fiocchi; Wesley Burks; Sami L Bahna; Leonard Bielory; Robert J Boyle; Renata Cocco; Sten Dreborg; Richard Goodman; Mikael Kuitunen; Tari Haahtela; Ralf G Heine; Gideon Lack; David A Osborn; Hugh Sampson; Gerald W Tannock; Bee Wah Lee
Journal:  World Allergy Organ J       Date:  2012-11       Impact factor: 4.084
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