Literature DB >> 9491253

Risk of cancer mortality among the Longitudinal Study of Astronaut Health (LSAH) participants.

P B Hamm1, R D Billica, G S Johnson, M L Wear, S L Pool.   

Abstract

BACKGROUND: The potential for occupational radiation exposures in the U.S. Space Program makes cancer risk a major health concern.
METHODS: The NASA Medical Operations Branch and KRUG Life Sciences Epidemiology Section at the Johnson Space Center (JSC) investigated the rate of cancer mortality among the astronauts and the comparison participants of the Longitudinal Study of Astronaut Health (LSAH). Medical records are maintained by the JSC Flight Medicine Clinic, JSC Occupational Medicine Clinic, and LSAH. Cause of death data from death certificates were reviewed for cancer mortality. These data were compared with cancer mortality data for the general population residing in the Texas Gulf Coast area.
RESULTS: The astronauts had a higher age-specific risk of cancer mortality than the comparison group (SMR = 345; 95% CI = 69.5-756.2), but the difference did not reach statistical significance. Both the astronauts and the comparison group had lower age-specific rates than the general population (SMR = 47, 95% CI = 9.6-105.1; SMR = 17, 95% CI = 3.5-37.9, respectively).

Entities:  

Keywords:  Non-programmatic

Mesh:

Year:  1998        PMID: 9491253

Source DB:  PubMed          Journal:  Aviat Space Environ Med        ISSN: 0095-6562


  6 in total

Review 1.  How does spaceflight affect the acquired immune system?

Authors:  Taishin Akiyama; Kenta Horie; Eiichi Hinoi; Manami Hiraiwa; Akihisa Kato; Yoichi Maekawa; Akihisa Takahashi; Satoshi Furukawa
Journal:  NPJ Microgravity       Date:  2020-05-07       Impact factor: 4.415

Review 2.  Space Radiation: The Number One Risk to Astronaut Health beyond Low Earth Orbit.

Authors:  Jeffery C Chancellor; Graham B I Scott; Jeffrey P Sutton
Journal:  Life (Basel)       Date:  2014-09-11

3.  Radiation Exposure and Mortality from Cardiovascular Disease and Cancer in Early NASA Astronauts.

Authors:  S Robin Elgart; Mark P Little; Lori J Chappell; Caitlin M Milder; Mark R Shavers; Janice L Huff; Zarana S Patel
Journal:  Sci Rep       Date:  2018-05-31       Impact factor: 4.379

4.  Apollo Lunar Astronauts Show Higher Cardiovascular Disease Mortality: Possible Deep Space Radiation Effects on the Vascular Endothelium.

Authors:  Michael D Delp; Jacqueline M Charvat; Charles L Limoli; Ruth K Globus; Payal Ghosh
Journal:  Sci Rep       Date:  2016-07-28       Impact factor: 4.379

5.  Adjustment of lifetime risks of space radiation-induced cancer by the healthy worker effect and cancer misclassification.

Authors:  Leif E Peterson; Tatiana Kovyrshina
Journal:  Heliyon       Date:  2015-12-22

Review 6.  How does spaceflight affect the acquired immune system?

Authors:  Taishin Akiyama; Kenta Horie; Eiichi Hinoi; Manami Hiraiwa; Akihisa Kato; Yoichi Maekawa; Akihisa Takahashi; Satoshi Furukawa
Journal:  NPJ Microgravity       Date:  2020-05-07       Impact factor: 4.415

  6 in total

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