Literature DB >> 949085

Experimental inhibition of prostaglandin-like inflammatory response after cryotherapy.

R M Chavis, C M Vygantas, A Vygantas.   

Abstract

To determine the effect of aspirin as an inhibitor of the prostaglandin-induced inflammatory reaction that follows cryotherapy, 12 rabbits were pretreated with aspirin and 12 were controls. The aspirin-pretreated animals showed less inflammatory reaction after cryotherapy and significantly less protein in the aqueous humor than did the control animals (P less than .01). We believe that the conjunctival hyperemia and chemosis, and the increase in protein concentrations in the aqueous humor that follow cryotherapy, are prostaglandin-related, because pretreatment with aspirin inhibited these phenomena.

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Year:  1976        PMID: 949085     DOI: 10.1016/0002-9394(76)90439-6

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  5 in total

1.  [Inhibition of secondary increase of intraocular pressure following cyclokryocoagulation (author's transl)].

Authors:  R Haddad; G Grabner; F Braun
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1979-05-07

2.  The developing bleb: effect of topical antiprostaglandins on the outcome of glaucoma fistulising surgery.

Authors:  C Migdal; R Hitchings
Journal:  Br J Ophthalmol       Date:  1983-10       Impact factor: 4.638

3.  Cyclocryokoagulation. Sequelae of induced alterations and effect of a prostaglandin-inhibitor on the breakdown of the blood-aqueous barrier.

Authors:  R Haddad; G Grabner; F Braun
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1980

4.  Mediation of the ocular response to cyclocryocoagulation.

Authors:  R Haddad; G Grabner; G Strasser; F Braun
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1981

5.  Dexamethasone and indomethacin attenuate cryopexy. Induced breakdown of the blood-retinal barrier.

Authors:  J H Stahl; D B Miller; B P Conway; P A Campochiaro
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1987       Impact factor: 3.117

  5 in total

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