Literature DB >> 9489495

Is ACTH a key to understanding anticonvulsant action?

M E O'Regan1, J K Brown.   

Abstract

Adrenocorticotrophin hormone (ACTH) has been used as an anticonvulsant for many years. In this paper, the use of ACTH in 23 children with intractable epilepsies is described. It was found that ACTH worked most effectively when the EEG showed benzodiazepine sensitivity. A mechanism of action of ACTH is proposed.

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Year:  1998        PMID: 9489495     DOI: 10.1111/j.1469-8749.1998.tb15366.x

Source DB:  PubMed          Journal:  Dev Med Child Neurol        ISSN: 0012-1622            Impact factor:   5.449


  2 in total

1.  How does metyrapone decrease seizures?

Authors:  C A Koch; S R Bornstein; K Pacak; G P Chrousos
Journal:  Neurosurg Rev       Date:  1998       Impact factor: 3.042

Review 2.  Corticosteroids in the management of the paediatric epilepsies.

Authors:  R Gupta; R Appleton
Journal:  Arch Dis Child       Date:  2005-04       Impact factor: 3.791

  2 in total

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