Literature DB >> 9489213

Derangement of warfarin anticoagulation by miconazole oral gel.

M N Pemberton1, P Sloan, S Ariyaratnam, N S Thakker, M H Thornhill.   

Abstract

The potentiation of the anticoagulant effects of warfarin by miconazole, when used in oral gel form, is described in three patients. The associated morbidity is examined, emphasising the importance of considering this potentially serious interaction when prescribing antifungal agents to patients on oral anticoagulants.

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Year:  1998        PMID： 9489213     DOI： 10.1038/sj.bdj.4809547

Source DB:  PubMed          Journal:  Br Dent J        ISSN： 0007-0610            Impact factor:   1.626


  4 in total

1.  Drug interactions in general dental practice--considerations for the dental practitioner.

Authors:  B E S Dawoud; A Roberts; J M Yates
Journal:  Br Dent J       Date:  2014-01       Impact factor: 1.626

Review 2.  Drug and dietary interactions of warfarin and novel oral anticoagulants: an update.

Authors:  Edith Nutescu; Ittiporn Chuatrisorn; Erika Hellenbart
Journal:  J Thromb Thrombolysis       Date:  2011-04       Impact factor: 2.300

3.  Morbidity and mortality associated with the interaction of miconazole oral gel and warfarin.

Authors:  M N Pemberton
Journal:  Br Dent J       Date:  2018-07-27       Impact factor: 1.626

4.  Voriconazole potentiates warfarin-induced prothrombin time prolongation.

Authors:  Lynn Purkins; Nolan Wood; Diane Kleinermans; Don Nichols
Journal:  Br J Clin Pharmacol       Date:  2003-12       Impact factor: 4.335
  4 in total

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