| Literature DB >> 9488625 |
T Miyamoto1, H Gondo, Y Miyoshi, H Shigematsu, T Minematsu, K Takenaka, K Tanimoto, T Horiuchi, Y Asano, S Inaba, Y Minamishima, Y Niho.
Abstract
A patient with non-Hodgkin's lymphoma who received a CD34-selected autologous peripheral blood stem cell transplant (PBSCT) developed cytomegalovirus retinitis, adenovirus-associated haemorrhagic cystitis (HC) and fatal herpes simplex virus pneumonia. Depletion of mature T cells from the graft and a persistent decrease in CD4+ lymphocytes following PBSCT may have predisposed this patient to such viral infections. Infusion of cryopreserved autologous PBSC (containing mature T cells) was effective for adenovirus-associated HC. Immunosuppression and resultant viral infections may affect patients receiving CD34-selected autologous transplantation.Entities:
Mesh:
Substances:
Year: 1998 PMID: 9488625 DOI: 10.1046/j.1365-2141.1998.00572.x
Source DB: PubMed Journal: Br J Haematol ISSN: 0007-1048 Impact factor: 6.998