| Literature DB >> 948758 |
G A Langer, J S Frank, L M Nudd, K Seraydarian.
Abstract
Specific removal of sialic acid from cultured heart cells with purified neuraminidase increases cellular calcium exchangeability. Potassium exchange is unaffected or slightly decreased. Sialic acid removal also permits lanthanum, normally restricted to the cellular surface, to enter the cells and displace more than 80 percent of cellular calcium. The results indicate a specific role of cellular surface components in the control of calcium exchangeability in the heart.Entities:
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Year: 1976 PMID: 948758 DOI: 10.1126/science.948758
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728