F Z Zhao1, M H Levy, S Wen. 1. Tuberculosis Control Project Office, Ministry of Health, Beijing, China.
Abstract
OBJECTIVE: To assess the importance of monitoring sputum conversion as an early treatment indicator of treatment success. METHODS: Retrospective analysis of sputum conversion in a cohort of 'cured' tuberculosis patients. RESULTS: Of 65 (95%) patients whose sputum converted in the third month of treatment, 62 were cured; only 21 of 35 (60%) patients whose sputum was still positive at the end of three months of treatment were ultimately cured. CONCLUSION: Sputum conversion during the third month of treatment is an important predictor of treatment success; failure to convert predicts treatment failure.
OBJECTIVE: To assess the importance of monitoring sputum conversion as an early treatment indicator of treatment success. METHODS: Retrospective analysis of sputum conversion in a cohort of 'cured' tuberculosispatients. RESULTS: Of 65 (95%) patients whose sputum converted in the third month of treatment, 62 were cured; only 21 of 35 (60%) patients whose sputum was still positive at the end of three months of treatment were ultimately cured. CONCLUSION: Sputum conversion during the third month of treatment is an important predictor of treatment success; failure to convert predicts treatment failure.
Authors: Christine Sekaggya-Wiltshire; Amrei von Braun; Mohammed Lamorde; Bruno Ledergerber; Allan Buzibye; Lars Henning; Joseph Musaazi; Ursula Gutteck; Paolo Denti; Miné de Kock; Alexander Jetter; Pauline Byakika-Kibwika; Nadia Eberhard; Joshua Matovu; Moses Joloba; Daniel Muller; Yukari C Manabe; Moses R Kamya; Natascia Corti; Andrew Kambugu; Barbara Castelnuovo; Jan S Fehr Journal: Clin Infect Dis Date: 2018-08-16 Impact factor: 9.079
Authors: David J Horne; Sarah E Royce; Lisa Gooze; Masahiro Narita; Philip C Hopewell; Payam Nahid; Karen R Steingart Journal: Lancet Infect Dis Date: 2010-06 Impact factor: 25.071