Literature DB >> 9486628

Independent technique of verifying high-dose rate (HDR) brachytherapy treatment plans.

C B Saw1, L J Korb, B Darnell, K V Krishna, D Ulewicz.   

Abstract

PURPOSE: An independent technique for verifying high-dose rate (HDR) brachytherapy treatment plans has been formulated and validated clinically. METHODS AND MATERIALS: In HDR brachytherapy, dwell times at respective dwell positions are computed, using an optimization algorithm in a HDR treatment-planning system to deliver a specified dose to many target points simultaneously. Because of the variability of dwell times, concerns have been expressed regarding the ability of the algorithm to compute the correct dose. To address this concern, a commercially available low-dose rate (LDR) algorithm was used to compute the doses at defined distances, based on the dwell times obtained from the HDR treatment plans. The percent deviation between doses computed using the HDR and LDR algorithms were reviewed for HDR procedures performed over the last year.
RESULTS: In this retrospective study, the difference between computed doses using the HDR and LDR algorithms was found to be within 5% for about 80% of the HDR procedures. All of the reviewed procedures have dose differences of less than 10%.
CONCLUSION: An independent technique for verifying HDR brachytherapy treatment plans has been validated based on clinical data. Provided both systems are available, this technique is universal in its applications and not limited to either a particular implant applicator, implant site, or implant type.

Mesh:

Year:  1998        PMID: 9486628     DOI: 10.1016/s0360-3016(97)00851-1

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  3 in total

1.  A method for checking high dose rate treatment times for vaginal applicators.

Authors:  C S Mayo; K Ulin
Journal:  J Appl Clin Med Phys       Date:  2001       Impact factor: 2.102

2.  A fast, independent dose check of HDR plans.

Authors:  Martin E Lachaine; Jason C Gorman; Madeline G Palisca
Journal:  J Appl Clin Med Phys       Date:  2003       Impact factor: 2.102

3.  Development of Volumetric Independent Dose Calculation System for Verification of the Treatment Plan in Image-Guided Adaptive Brachytherapy.

Authors:  Sang-Won Kang; Jin-Beom Chung; Kyeong-Hyeon Kim; Ji-Yeon Park; Hae-Jin Park; Woong Cho; Sven Olberg; Tae Suk Suh; Justin C Park
Journal:  Front Oncol       Date:  2020-05-13       Impact factor: 6.244

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.