Literature DB >> 9481547

Rare case of autoimmune hyperchylomicronemia during pregnancy.

T Yoshimura1, M Ito, Y Sakoda, S Kobori, H Okamura.   

Abstract

A pregnant woman was found to have severe hypertriglyceridemia, fasting chylomicronemia, and low platelet count. The activities of serum lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL) proved to be extremely low. The activities of the enzymes in normal plasma were completely inhibited by addition of the patient's plasma. We concluded that autoantibodies to lipases were responsible for this patient's hypertriglyceridemia.

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Year:  1998        PMID： 9481547     DOI： 10.1016/s0301-2115(97)00154-1

Source DB:  PubMed          Journal:  Eur J Obstet Gynecol Reprod Biol        ISSN： 0301-2115            Impact factor:   2.435


  3 in total

1.  Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.

Authors:  Anne P Beigneux; Kazuya Miyashita; Michael Ploug; Dirk J Blom; Masumi Ai; MacRae F Linton; Weerapan Khovidhunkit; Robert Dufour; Abhimanyu Garg; Maureen A McMahon; Clive R Pullinger; Norma P Sandoval; Xuchen Hu; Christopher M Allan; Mikael Larsson; Tetsuo Machida; Masami Murakami; Karen Reue; Peter Tontonoz; Ira J Goldberg; Philippe Moulin; Sybil Charrière; Loren G Fong; Katsuyuki Nakajima; Stephen G Young
Journal:  N Engl J Med       Date:  2017-04-05       Impact factor: 91.245

2.  Type 1 hyperlipoproteinemia and recurrent acute pancreatitis due to lipoprotein lipase antibody in a young girl with Sjogren's syndrome.

Authors:  Ambika P Ashraf; Timothy Beukelman; Valerie Pruneta-Deloche; David R Kelly; Abhimanyu Garg
Journal:  J Clin Endocrinol Metab       Date:  2011-08-31       Impact factor: 5.958

3.  A case of non-alcoholic steatohepatitis complicated with severe acute pancreatitis induced by decreased lipoprotein lipase and hepatic triglyceride lipase activity levels in a young Japanese woman.

Authors:  Sawa Minohara; Sung Kwan Bae; Saori Sugiyama; Noriko Shibata; Toshifumi Gushima; Junichi Motoshita; Shinji Shimoda; Atsuko Takagi; Yasuyuki Ikeda; Kazuhiro Takahashi
Journal:  Clin Case Rep       Date:  2018-07-18
  3 in total

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