Literature DB >> 947845

Inhibition of human neutrophil chemotaxis and chemiluminescence by amphotericin B.

B Björkstén, C Ray, P G Quie.   

Abstract

The effect of the antifungal drugs amphotericin B, fluocytosine, miconazole, griseofulvin, and nystatin on the chemotactic responsiveness of human neutrophils was studied. Amphotericin B in a concentration of 2 mug/ml inhibited chemotatic responsiveness, and in a concentration of 5 mug/ml it also inhibited chemiluminescence. The inhibition of chemotaxis could be reversed by washing the cells. The other antifungal drugs did not inhibit chemotaxis even in concentrations much higher than those obtained in human serum during treatment.

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Year:  1976        PMID： 947845      PMCID： PMC420880          DOI： 10.1128/iai.14.1.315-317.1976

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  8 in total

1.  Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leukocytes and monocytes.

Authors:  R D Nelson; P G Quie; R L Simmons
Journal:  J Immunol       Date:  1975-12       Impact factor: 5.422

2.  Modulation of human neutrophil chemotactic responses by cyclic 3',5'-guanosine monophosphate and cyclic 3',5'-adenosine monophosphate.

Authors:  H R Hill; R D Estensen; P G Quie; N A Hogan; N D Goldberg
Journal:  Metabolism       Date:  1975-03       Impact factor: 8.694

3.  Effects of 5-fluorocytosine on protein synthesis and amino acid pool in Candida albicans.

Authors:  A Polak
Journal:  Sabouraudia       Date:  1974-11

4.  Effect of tetracycline on the phagocytic function of human leukocytes.

Authors:  A Forsgren; D Schmeling; P G Quie
Journal:  J Infect Dis       Date:  1974-10       Impact factor: 5.226

5.  The ultrastructure of Candida albicans after in vitro treatment with miconazole.

Authors:  S De Nollin; M Borgers
Journal:  Sabouraudia       Date:  1974-11

6.  Effects of tetracycline on leukotaxis.

Authors:  R R Martin; G A Warr; R B Couch; H Yeager; V Knight
Journal:  J Infect Dis       Date:  1974-02       Impact factor: 5.226

7.  Evidence for the generation of an electronic excitation state(s) in human polymorphonuclear leukocytes and its participation in bactericidal activity.

Authors:  R C Allen; R L Stjernholm; R H Steele
Journal:  Biochem Biophys Res Commun       Date:  1972-05-26       Impact factor: 3.575

8.  Inhibition by sulfonamides of the candidacidal activity of human neutrophils.

Authors:  R I Lehrer
Journal:  J Clin Invest       Date:  1971-12       Impact factor: 14.808
  8 in total
  15 in total

1.  Enhancement of macrophage superoxide anion production by amphotericin B.

Authors:  E Wilson; L Thorson; D P Speert
Journal:  Antimicrob Agents Chemother       Date:  1991-05       Impact factor: 5.191

2.  Neutrophil toxicity of amphotericin B.

Authors:  C J Chunn; P R Starr; D N Gilbert
Journal:  Antimicrob Agents Chemother       Date:  1977-08       Impact factor: 5.191

3.  Lipid complexing decreases amphotericin B inflammatory activation of human neutrophils compared with that of a desoxycholate-suspended preparation of amphotericin B (Fungizone).

Authors:  G W Sullivan; H T Carper; G L Mandell
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

4.  Interference of granulocyte function by the vehicle of miconazole.

Authors:  C Lee; E G Maderazo
Journal:  Antimicrob Agents Chemother       Date:  1978-03       Impact factor: 5.191

5.  Influence of antibiotics on formylmethionyl-leucyl-phenylalanine-induced leukocyte chemiluminescence.

Authors:  G Briheim; C Dahlgren
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

6.  Influence of six antifungal agents on the chemiluminescence response of mouse spleen cells.

Authors:  G K Abruzzo; D M Giltinan; T P Capizzi; R A Fromtling
Journal:  Antimicrob Agents Chemother       Date:  1986-04       Impact factor: 5.191

7.  Stimulation of human and canine neutrophil metabolism by amphotericin B.

Authors:  S R Supapidhayakul; L R Kizlaitis; B R Andersen
Journal:  Antimicrob Agents Chemother       Date:  1981-02       Impact factor: 5.191

8.  Effects of naftifine and terbinafine, two allylamine antifungal drugs, on selected functions of human polymorphonuclear leukocytes.

Authors:  T Vago; G Baldi; D Colombo; M Barbareschi; G Norbiato; F Dallegri; M Bevilacqua
Journal:  Antimicrob Agents Chemother       Date:  1994-11       Impact factor: 5.191

9.  Miconazole and amphotericin B alter polymorphonuclear leukocyte functions and membrane fluidity in similar fashions.

Authors:  K Yasui; M Masuda; T Matsuoka; M Yamazaki; A Komiyama; T Akabane; K Murata
Journal:  Antimicrob Agents Chemother       Date:  1988-12       Impact factor: 5.191

10.  Pulmonary complications in patients receiving granulocyte transfusions and amphotericin B.

Authors:  E J Bow; M L Schroeder; T J Louie
Journal:  Can Med Assoc J       Date:  1984-03-01       Impact factor: 8.262
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