Literature DB >> 947832

Steroid derivatives. LXXIX. Microbial 15 beta-hydroxylation of 17 alpha-acetoxy-16-methylene derivatives of the pregnane series by the action of Cunninghamella blakesleeana.

R Mícková, J Protiva, V Schwarz.   

Abstract

Hydroxylation of 17 alpha-acetoxy-6-chloro-16-methylene-4,6-pregnadiene-3,20-dione (Chlorosuperlutin, I) by Cunninghamella blakesleeana yielded a 15 beta-hydroxyderivative II. Analogous transformation of 17 alpha-acetoxy-16-methylene-4,6-pregnadiene-3,20-dione (Superlutin, IV) included a hydroxylation in position 15 beta and probably also in 11 beta with a concomitant reduction of the 6,7-double bond.

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Year:  1976        PMID： 947832     DOI： 10.1007/bf02876982

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  3 in total

1.  [STUDIES IN THE FIELD OF MICROBIOLOGICAL TRANSFORMATIONS. XX. HYDROXYLATION OF PROGESTERONE BY SYNCEPHALASTRUM RACEMOSUM COHN (5)].

Authors:  Y SATO; T TANAKA; M KATO; K TSUDA
Journal:  Chem Pharm Bull (Tokyo)       Date:  1963-12       Impact factor: 1.645

2.  SUBSTRATE SPECIFICITY IN STEROID SIDE-CHAIN DEGRADATION BY MICROORGANISMS.

Authors:  O EL-TAYEB; S G KNIGHT; C J SIH
Journal:  Biochim Biophys Acta       Date:  1964-11-08

3.  Microbial transformation of steroids. XVII. Transformation of progesterone by various species and strains of Penicillium.

Authors:  A CAPEK; O HANC
Journal:  Folia Microbiol (Praha)       Date:  1962-03       Impact factor: 2.099
  3 in total

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