| Literature DB >> 9477341 |
A C Ivens1, S M Lewis, A Bagherzadeh, L Zhang, H M Chan, D F Smith.
Abstract
An extensive physical map of the Leishmania major Friedlin genome has been assembled by the combination of fingerprint analysis of a shuttle vector cosmid library and probe hybridization. The integrated data obtained for 9004 fingerprinted clones and 974 probes have placed 91.2% of the 33.58-Mb genome into contigs representing each of the 36 chromosomes. This first-generation map has already provided a suitable framework for both high-throughput DNA sequencing and functional studies of the L. major parasite.Entities:
Mesh:
Substances:
Year: 1998 PMID: 9477341 PMCID: PMC310692 DOI: 10.1101/gr.8.2.135
Source DB: PubMed Journal: Genome Res ISSN: 1088-9051 Impact factor: 9.043