Literature DB >> 9468639

Synthesis and biological evaluation of flavanones and flavones related to podophyllotoxin.

A Gonzalez De Peredo1, S Léonce, C Monneret, D Dauzonne.   

Abstract

A series of novel flavonoids comprising structural elements present in the antineoplastic agents podophyllotoxin and etoposide was synthesized. These oxygen-containing analogues of antiproliferative quinolones moderate cytotoxicity towards L1210 and HT-29 cell lines.

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Year:  1998        PMID： 9468639     DOI： 10.1248/cpb.46.79

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  2 in total

1.  Analogues of doxanthrine reveal differences between the dopamine D1 receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines.

Authors:  Juan Pablo Cueva; Benjamin R Chemel; Jose I Juncosa; Markus A Lill; Val J Watts; David E Nichols
Journal:  Eur J Med Chem       Date:  2011-12-03       Impact factor: 6.514

2.  Synthesis and biological evaluation of 3-nitro-4-chromanone derivatives as potential antiproliferative agents for castration-resistant prostate cancer.

Authors:  Huiqing Chen; Yajing Xing; Jia Xie; Jiuqing Xie; Dong Xing; Jie Tang; Fan Yang; Zhengfang Yi; Wen-Wei Qiu
Journal:  RSC Adv       Date:  2019-10-21       Impact factor: 4.036
  2 in total

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