Literature DB >> 9468581

Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.

T J Chang1, C C Juan, P H Yin, C W Chi, H J Tsay.   

Abstract

Beta-actin, cyclophilin and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) are all constantly expressed proteins that regulate cellular structures and endogenous cytoarchitectural functions. In this study, we used an in vivo N1S1 rat hepatoma model to examine changes in the expression levels of these housekeeping genes in normal and tumor liver samples. The beta-actin, cyclophilin and GAPDH genes were all up-regulated in tumor groups as compared to the controls. Our results suggest that up-regulation of beta-actin, cyclophilin and GAPDH genes may be essential for oncogenesis in hepatoma.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9468581     DOI： 10.3892/or.5.2.469

Source DB:  PubMed          Journal:  Oncol Rep        ISSN： 1021-335X            Impact factor:   3.906


  20 in total

1.  A new mathematical model for relative quantification in real-time RT-PCR.

Authors:  M W Pfaffl
Journal:  Nucleic Acids Res       Date:  2001-05-01       Impact factor: 16.971

2.  Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR.

Authors:  Michael W Pfaffl; Graham W Horgan; Leo Dempfle
Journal:  Nucleic Acids Res       Date:  2002-05-01       Impact factor: 16.971

3.  Systematic method for determining an ideal housekeeping gene for real-time PCR analysis.

Authors:  Viraj P Mane; Melissa A Heuer; Philippa Hillyer; Maria B Navarro; Ronald L Rabin
Journal:  J Biomol Tech       Date:  2008-12

4.  Development of a quantitative assay for SARS coronavirus and correlation of GAPDH mRNA with SARS coronavirus in clinical specimens.

Authors:  S C C Wong; J K C Chan; K C Lee; E S F Lo; D N C Tsang
Journal:  J Clin Pathol       Date:  2005-03       Impact factor: 3.411

5.  Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues.

Authors:  Hua He; Fangyan Dai; Long Yu; Xingyu She; Yong Zhao; Jianmin Jiang; Xiaosong Chen; Shouyuan Zhao
Journal:  Gene Expr       Date:  2002

6.  Housekeeping genes as internal standards in cancer research.

Authors:  Nico Janssens; Michel Janicot; Tim Perera; Annette Bakker
Journal:  Mol Diagn       Date:  2004

7.  A network-based maximum link approach towards MS identifies potentially important roles for undetected ARRB1/2 and ACTB in liver cancer progression.

Authors:  Wilson Wen Bin Goh; Yie Hou Lee; Zubaidah M Ramdzan; Maxey C M Chung; Limsoon Wong; Marek J Sergot
Journal:  Int J Bioinform Res Appl       Date:  2012

8.  Differential expression of GAPDH and beta3-actin in growing collateral arteries.

Authors:  Elisabeth Deindl; Kerstin Boengler; Niels van Royen; Wolfgang Schaper
Journal:  Mol Cell Biochem       Date:  2002-07       Impact factor: 3.396

9.  A protein-based set of reference markers for liver tissues and hepatocellular carcinoma.

Authors:  Stella Sun; Xin Yi; Ronnie Tp Poon; Chun Yeung; Philip J R Day; John M Luk
Journal:  BMC Cancer       Date:  2009-09-02       Impact factor: 4.430

10.  MALDI profiling of human lung cancer subtypes.

Authors:  Angelo Gámez-Pozo; Iker Sánchez-Navarro; Manuel Nistal; Enrique Calvo; Rosario Madero; Esther Díaz; Emilio Camafeita; Javier de Castro; Juan Antonio López; Manuel González-Barón; Enrique Espinosa; Juan Angel Fresno Vara
Journal:  PLoS One       Date:  2009-11-05       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.