Literature DB >> 9468322

Resveratrol, a remarkable inhibitor of ribonucleotide reductase.

M Fontecave1, M Lepoivre, E Elleingand, C Gerez, O Guittet.   

Abstract

Resveratrol, a natural phytoalexin found in grapes, is well known for its presumed role in the prevention of heart disease, associated with red wine consumption. We show here that it is a remarkable inhibitor of ribonucleotide reductase and DNA synthesis in mammalian cells, which might have further applications as an antiproliferative or a cancer chemopreventive agent in humans.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9468322     DOI： 10.1016/s0014-5793(97)01572-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  60 in total

1.  Identification and purification of resveratrol targeting proteins using immobilized resveratrol affinity chromatography.

Authors:  Zhirong Wang; Tze-chen Hsieh; Zhongtao Zhang; Yuliang Ma; Joseph M Wu
Journal:  Biochem Biophys Res Commun       Date:  2004-10-22       Impact factor: 3.575

Review 2.  Resveratrol and resveratrol analogues--structure-activity relationship.

Authors:  Thomas Szekeres; Monika Fritzer-Szekeres; Philipp Saiko; Walter Jäger
Journal:  Pharm Res       Date:  2010-03-16       Impact factor: 4.200

3.  Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma.

Authors:  Paula Ferrer; Miguel Asensi; Ramón Segarra; Angel Ortega; María Benlloch; Elena Obrador; María T Varea; Gregorio Asensio; Leonardo Jordá; José M Estrela
Journal:  Neoplasia       Date:  2005-01       Impact factor: 5.715

4.  5,6-Dihydro-5-aza-2'-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors.

Authors:  Jonathan M Rawson; Richard H Heineman; Lauren B Beach; Jessica L Martin; Erica K Schnettler; Michael J Dapp; Steven E Patterson; Louis M Mansky
Journal:  Bioorg Med Chem       Date:  2013-08-20       Impact factor: 3.641

5.  Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells.

Authors:  Francesca De Amicis; Francesca Giordano; Adele Vivacqua; Michele Pellegrino; Maria Luisa Panno; Donatella Tramontano; Suzanne A W Fuqua; Sebastiano Andò
Journal:  FASEB J       Date:  2011-07-07       Impact factor: 5.191

6.  Targeting host nucleotide biosynthesis with resveratrol inhibits emtricitabine-resistant HIV-1.

Authors:  Alonso Heredia; Charles Davis; Mohammed N Amin; Nhut M Le; Mark A Wainberg; Maureen Oliveira; Steven G Deeks; Lai-Xi Wang; Robert R Redfield
Journal:  AIDS       Date:  2014-01-28       Impact factor: 4.177

Review 7.  Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms.

Authors:  Mohammad Athar; Jung Ho Back; Levy Kopelovich; David R Bickers; Arianna L Kim
Journal:  Arch Biochem Biophys       Date:  2009-06-15       Impact factor: 4.013

8.  Resveratrol attenuates inflammation and stricture formation in experimental caustic esophageal burns.

Authors:  S Uguralp; C Irsi; T Aksoy; A Bay Karabulut; H Kirimlioglu; B Mizrak
Journal:  Pediatr Surg Int       Date:  2008-02-19       Impact factor: 1.827

9.  Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro.

Authors:  S Madlener; P Saiko; C Vonach; K Viola; N Huttary; N Stark; R Popescu; M Gridling; N T-P Vo; I Herbacek; A Davidovits; B Giessrigl; S Venkateswarlu; S Geleff; W Jäger; M Grusch; D Kerjaschki; W Mikulits; T Golakoti; M Fritzer-Szekeres; T Szekeres; G Krupitza
Journal:  Br J Cancer       Date:  2010-04-27       Impact factor: 7.640

10.  Crystal structure of quinone reductase 2 in complex with resveratrol.

Authors:  Leonid Buryanovskyy; Yue Fu; Molly Boyd; Yuliang Ma; Tze-chen Hsieh; Joseph M Wu; Zhongtao Zhang
Journal:  Biochemistry       Date:  2004-09-14       Impact factor: 3.162
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.