OBJECTIVE: Our purpose was to compare induction of labor with preterm rupture of membranes between 34 and 37 weeks' gestation with expectant management. STUDY DESIGN: In this prospective investigation 120 gravid women at > or = 34 weeks 0 days and < 36 weeks 6 days of gestation were randomized to receive oxytocin induction (n = 57) or observation (n = 63). RESULTS:Estimated gestational age at rupture of membranes (34.3 +/- 1.4 weeks vs 34.5 +/- 1.4 weeks) and ultrasonographically estimated fetal weight (2230 +/- 321 gm vs 2297 +/- 365 gm) were equivalent between groups (not significant). Chorioamnionitis occurred more often (16% vs 2%, p = 0.007), and maternal hospital stay (5.2 +/- 6.8 days vs 2.6 +/- 1.6 days, p = 0.006) was significantly longer in the control group. Neonatal sepsis was also more common in the observation group (n = 3) than among induction patients (n = 0), but the difference was not statistically significant. CONCLUSION: Aggressive management of preterm premature rupture of the membranes at > or = 34 weeks 0 days of gestation by induction of labor is safe for the infant in our population and avoids maternal-neonatal infectious complications.
RCT Entities:
OBJECTIVE: Our purpose was to compare induction of labor with preterm rupture of membranes between 34 and 37 weeks' gestation with expectant management. STUDY DESIGN: In this prospective investigation 120 gravid women at > or = 34 weeks 0 days and < 36 weeks 6 days of gestation were randomized to receive oxytocin induction (n = 57) or observation (n = 63). RESULTS: Estimated gestational age at rupture of membranes (34.3 +/- 1.4 weeks vs 34.5 +/- 1.4 weeks) and ultrasonographically estimated fetal weight (2230 +/- 321 gm vs 2297 +/- 365 gm) were equivalent between groups (not significant). Chorioamnionitis occurred more often (16% vs 2%, p = 0.007), and maternal hospital stay (5.2 +/- 6.8 days vs 2.6 +/- 1.6 days, p = 0.006) was significantly longer in the control group. Neonatal sepsis was also more common in the observation group (n = 3) than among induction patients (n = 0), but the difference was not statistically significant. CONCLUSION: Aggressive management of preterm premature rupture of the membranes at > or = 34 weeks 0 days of gestation by induction of labor is safe for the infant in our population and avoids maternal-neonatal infectious complications.
Authors: Diana M Bond; Philippa Middleton; Kate M Levett; David P van der Ham; Caroline A Crowther; Sarah L Buchanan; Jonathan Morris Journal: Cochrane Database Syst Rev Date: 2017-03-03
Authors: Rían Hayes; Jack Hartnett; Gergana Semova; Cian Murray; Katherine Murphy; Leah Carroll; Helena Plapp; Louise Hession; Jonathan O'Toole; Danielle McCollum; Edna Roche; Elinor Jenkins; David Mockler; Tim Hurley; Matthew McGovern; John Allen; Judith Meehan; Frans B Plötz; Tobias Strunk; Willem P de Boode; Richard Polin; James L Wynn; Marina Degtyareva; Helmut Küster; Jan Janota; Eric Giannoni; Luregn J Schlapbach; Fleur M Keij; Irwin K M Reiss; Joseph Bliss; Joyce M Koenig; Mark A Turner; Christopher Gale; Eleanor J Molloy Journal: Pediatr Res Date: 2021-11-06 Impact factor: 3.756
Authors: Catalin S Buhimschi; Sonya Abdel-Razeq; Michael Cackovic; Christian M Pettker; Antonette T Dulay; Mert Ozan Bahtiyar; Eduardo Zambrano; Ryan Martin; Errol R Norwitz; Vineet Bhandari; Irina A Buhimschi Journal: Am J Perinatol Date: 2008-05-29 Impact factor: 1.862
Authors: Antonette T Dulay; Irina A Buhimschi; Guomao Zhao; Guoyang Luo; Sonya Abdel-Razeq; Michael Cackovic; Victor A Rosenberg; Christian M Pettker; Stephen F Thung; Mert O Bahtiyar; Vineet Bhandari; Catalin S Buhimschi Journal: Am J Obstet Gynecol Date: 2008-04 Impact factor: 8.661
Authors: Catalin S Buhimschi; Vineet Bhandari; Antonette T Dulay; Unzila A Nayeri; Sonya S Abdel-Razeq; Christian M Pettker; Stephen Thung; Guomao Zhao; Yiping W Han; Matthew Bizzarro; Irina A Buhimschi Journal: PLoS One Date: 2011-10-10 Impact factor: 3.240
Authors: David P van der Ham; Sylvia M C Vijgen; Jan G Nijhuis; Johannes J van Beek; Brent C Opmeer; Antonius L M Mulder; Rob Moonen; Mariët Groenewout; Mariëlle G van Pampus; Gerald D Mantel; Kitty W M Bloemenkamp; Wim J van Wijngaarden; Marko Sikkema; Monique C Haak; Paula J M Pernet; Martina Porath; Jan F M Molkenboer; Simone Kuppens; Anneke Kwee; Michael E Kars; Mallory Woiski; Martin J N Weinans; Hajo I J Wildschut; Bettina M C Akerboom; Ben W J Mol; Christine Willekes Journal: PLoS Med Date: 2012-04-24 Impact factor: 11.069