Literature DB >> 9463987

Adrenaline degradation in general practice.

S V Rudland1, T Annus, J Dickinson, S Langdon.   

Abstract

The general practitioner's (GP's) doctor's bag is exposed to extreme temperatures that may affect the stability of the drugs it contains. Adrenaline (1:1000 solution) is more stable than previous studies would suggest. GPs carry out-of-date drugs despite stating that they regularly check expiry dates.

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Year:  1997        PMID: 9463987      PMCID: PMC1410066     

Source DB:  PubMed          Journal:  Br J Gen Pract        ISSN: 0960-1643            Impact factor:   5.386


  9 in total

1.  Visiting bags: a labile thermal environment.

Authors:  S V Rudland; A G Jacobs
Journal:  BMJ       Date:  1994-04-09

2.  Emergency care in general practice.

Authors:  A Avery; M Pringle
Journal:  BMJ       Date:  1995-01-07

3.  Stability of epinephrine in dental anesthetic solutions: implications for autoclave sterilization and elevated temperature storage.

Authors:  J R Kelly; G W Dalm
Journal:  Mil Med       Date:  1985-02       Impact factor: 1.437

4.  Modified sample preparation for high-performance liquid chromatographic--electrochemical assay of urinary catecholamines.

Authors:  D S Goldstein
Journal:  J Chromatogr       Date:  1983-06-10

5.  Storage at body temperature alters concentration of vasoconstrictors in local anesthetics.

Authors:  B W Fry; A E Ciarlone
Journal:  J Dent Res       Date:  1980-06       Impact factor: 6.116

6.  Concentrations of vasoconstrictors in local anesthetics change during storage in cartridge heaters.

Authors:  B W Fry; A E Ciarlone
Journal:  J Dent Res       Date:  1980-07       Impact factor: 6.116

7.  Environmental temperature variations cause degradations in epinephrine concentration and biological activity.

Authors:  T A Grant; R G Carroll; W H Church; A Henry; N H Prasad; A A Abdel-Rahman; E J Allison
Journal:  Am J Emerg Med       Date:  1994-05       Impact factor: 2.469

8.  Thermal degradation of injectable epinephrine.

Authors:  W H Church; S S Hu; A J Henry
Journal:  Am J Emerg Med       Date:  1994-05       Impact factor: 2.469

9.  Functional effects of adrenochrome in isolated rabbit heart.

Authors:  A F Rump; W Klaus
Journal:  Pharmacol Toxicol       Date:  1995-08
  9 in total
  1 in total

1.  Keep in a cool place: exposure of medicines to high temperatures in general practice during a British heatwave.

Authors:  Brian Crichton
Journal:  J R Soc Med       Date:  2004-07       Impact factor: 18.000

  1 in total

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