| Literature DB >> 9463677 |
T H Duong1, M Kombila, A Ferrer, P Bureau, P Gaxotte, D Richard-Lenoble.
Abstract
The action of a single dose of ivermectin (200 micrograms/kg) on 71 Gabonese patients with Loa loa microfilariae in the peripheral blood, and living in areas highly endemic for loiasis, has been evaluated. Ten to 12 months after treatment, 43 patients (63%) had no circulating microfilaria and the geometric mean peripheral blood microfilaria count had decreased by 88.6% (P < 0.02). Thus, a single annual dose of ivermectin can markedly reduce loiasis transmission.Entities:
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Year: 1997 PMID： 9463677 DOI： 10.1016/s0035-9203(97)90040-7
Source DB: PubMed Journal: Trans R Soc Trop Med Hyg ISSN： 0035-9203 Impact factor: 2.184