Literature DB >> 9462552

Deep-vein thrombosis and coumarin skin necrosis associated with a factor V inhibitor with lupus-like features.

P W Kamphuisen1, J Haan, P C Rosekrans, F J Van Der Meer.   

Abstract

We report a 71-year-old man who developed deep-vein thrombosis after major surgery. Coumarin skin necrosis developed after starting oral anticoagulant therapy. An inhibitor to factor V (61 Bethesda units) with lupus-like features was found as well as a low protein C level. The occurrence of these very rare findings indicates that despite profound procoagulant inhibition (factor V inhibition and anticoagulant therapy), hypercoagulation can occur.

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Year:  1998        PMID： 9462552     DOI： 10.1002/(sici)1096-8652(199802)57:2<176::aid-ajh14>3.0.co;2-a

Source DB:  PubMed          Journal:  Am J Hematol        ISSN： 0361-8609            Impact factor:   10.047


  8 in total

Review 1.  Acquired factor V inhibitors: a systematic review.

Authors:  Massimo Franchini; Giuseppe Lippi
Journal:  J Thromb Thrombolysis       Date:  2011-05       Impact factor: 2.300

2.  Acquired factor V inhibitor associated with valproic acid use in a cirrhotic patient.

Authors:  B Godart; C Boinot; C Remblier; A Hajjar; M Beauchant
Journal:  Gut       Date:  2006-01       Impact factor: 23.059

3.  Transient cefuroxime/metronidazole treatment induced factor V antibodies.

Authors:  Sjoerd Adrianus Antonius Van den Berg; Patricia E Verwer; René N Idema; Coen Van Guldener
Journal:  BMJ Case Rep       Date:  2014-08-19

4.  Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin.

Authors:  T L Ortel; M C Mercer; E H Thames; K D Moore; J H Lawson
Journal:  Ann Surg       Date:  2001-01       Impact factor: 12.969

5.  A high titer of acquired factor V inhibitor in a hemodialysis patient who developed arterial thrombosis.

Authors:  Hina Ogawa; Masayoshi Souri; Kazunori Kanouchi; Tsukasa Osaki; Rie Ohkubo; Tomoko Kawanishi; Sachiko Wakai; Keita Morikane; Akitada Ichinose
Journal:  Int J Hematol       Date:  2018-11-16       Impact factor: 2.490

6.  Bleeding associated with acquired factor V inhibitor in a patient on warfarin treated successfully with prednisolone.

Authors:  Alhossain Khalafallah; Julian Grabek; Robert Hayes; Muhajir Mohamed
Journal:  BMJ Case Rep       Date:  2013-08-06

7.  Acquired factor V inhibitor in a patient with mantle cell lymphoma presenting with hematuria followed by thrombosis: a case report.

Authors:  Naif I Aljohani; John H Matthews
Journal:  Int Med Case Rep J       Date:  2014-02-24

8.  Acquired factor V deficiency in a patient with a urinary tract infection presenting with haematuria followed by multiple haemorrhages with an extremely low level of factor V inhibitor: a case report and review of the literature.

Authors:  Xiangyu Wang; Xuemei Qin; Yuan Yu; Ran Wang; Xinguang Liu; Min Ji; Minran Zhou; Chunyan Chen
Journal:  Blood Coagul Fibrinolysis       Date:  2017-06       Impact factor: 1.276
  8 in total

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