| Literature DB >> 9461664 |
H Doug1, S X Chen, H X Xu, S Kadota, T Namba.
Abstract
A new diarylheptanoid, 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one (1), along with seven other known compounds, were isolated from the seeds of Alpinia blepharocalyx. Of these, compounds 1 and 3 showed strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. Compound 3 also strongly inhibited ristocetin-induced platelet aggregation. Structures of these compounds were elucidated by spectroscopic and chemical means.Entities:
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Year: 1998 PMID： 9461664 DOI： 10.1021/np970293i
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050