| Literature DB >> 9461087 |
B J Mathis1, S H Kim, K Calabrese, M Haas, J G Seidman, C E Seidman, M R Pollak.
Abstract
We performed a genome-wide linkage analysis search for a genetic locus responsible for kidney dysfunction in a large family. This inherited condition, characterized by proteinuria, progressive renal insufficiency, and focal segmental glomerulosclerosis, follows autosomal dominant inheritance. We show with a high degree of certainty (maximum 2-point lod score 12.28) that the gene responsible for this condition is located on chromosome 19q13.Entities:
Mesh：
Year: 1998 PMID： 9461087 DOI： 10.1046/j.1523-1755.1998.00828.x
Source DB: PubMed Journal: Kidney Int ISSN： 0085-2538 Impact factor: 10.612