Literature DB >> 9460147

Simulation of whiplash trauma using whole cervical spine specimens.

M M Panjabi1, J Cholewicki, K Nibu, L B Babat, J Dvorak.   

Abstract

STUDY
DESIGN: Whiplash injuries were studied in an experiment using whole cervical spine specimen.
OBJECTIVES: To develop a whiplash trauma model that uses a whole cervical spine specimen, and to show the feasibility and unique features of such a model. SUMMARY OF BACKGROUND DATA: Whiplash trauma has been simulated in biomechanical experiments using volunteers, whole body cadavers, animals, anthropometric dummies, and mathematic models. These experiments require large facilities, are expensive, and provide limited information about cervical spine injuries.
METHODS: An alternate approach, in which a bench-top sled accelerating apparatus is used to produce whiplash trauma, has been developed to study such trauma in whole cervical spine specimens. Several transducers were developed to monitor soft tissue injuries during the trauma. The model also provides quantification of injuries to the cervical spine.
RESULTS: To assess the feasibility and usefulness of the model, a specimen was traumatized, and the following parameters were monitored during the trauma: linear acceleration of the sled, linear and angular acceleration of the head surrogate, displacements of the head surrogate, loads at T1 and C1 vertebrae, and linear deformations of capsular ligaments and vertebral artery.
CONCLUSIONS: This model, which incorporates a fresh cadaveric whole human cervical spine specimen, can simulate whiplash trauma effectively and is useful in providing a comprehensive set of clinically relevant information during the trauma. This model gives insight into the complex events and interactions that cause the injuries that occur during whiplash trauma.

Entities:  

Mesh:

Year:  1998        PMID: 9460147     DOI: 10.1097/00007632-199801010-00005

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  24 in total

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3.  Biofidelic whole cervical spine model with muscle force replication for whiplash simulation.

Authors:  P C Ivancic; Manohar M Panjabi; S Ito; P A Cripton; J L Wang
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4.  Cervical facet joint kinematics during bilateral facet dislocation.

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5.  Activating transcription factor 4, a mediator of the integrated stress response, is increased in the dorsal root ganglia following painful facet joint distraction.

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6.  Dynamic elongation of the vertebral artery during an in vitro whiplash simulation.

Authors:  K Nibu; J Cholewicki; M M Panjabi; L B Babat; J N Grauer; R Kothe; J Dvorak
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7.  Kinematic Comparison of Pediatric Human Volunteers and the Hybrid III 6-Year-Old Anthropomorphic Test Device.

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8.  Physiologic facet capsule stretch can induce pain & upregulate matrix metalloproteinase-3 in the dorsal root ganglia when preceded by a physiological mechanical or nonpainful chemical exposure.

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9.  Simulated whiplash modulates expression of the glutamatergic system in the spinal cord suggesting spinal plasticity is associated with painful dynamic cervical facet loading.

Authors:  Ling Dong; Beth A Winkelstein
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10.  Painful facet joint injury induces neuronal stress activation in the DRG: implications for cellular mechanisms of pain.

Authors:  Ling Dong; Akinleye O Odeleye; Kelly L Jordan-Sciutto; Beth A Winkelstein
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