Literature DB >> 9459302

Identification of Myo3, a second type-II myosin heavy chain in the fission yeast Schizosaccharomyces pombe.

F Motegi1, K Nakano, C Kitayama, M Yamamoto, I Mabuchi.   

Abstract

We cloned the myo3+ gene of Schizosaccharomyces pombe which encodes a type-II myosin heavy chain. myo3 null cells showed a defect in cytokinesis under certain conditions. Overproduction of Myo3 also showed a defect in cytokinesis. Double mutant analysis indicated that Myo3 genetically interacts with Cdc8 tropomyosin and actin. Myo3 may be implicated in cytokinesis and stabilization of F-actin cables. Moreover, the function of Myo2 can be replaced by overexpressed Myo3. We observed a modest synthetic interaction between Myo2 and Myo3. Thus, Myo2 and Myo3 seem to cooperate in the formation of the F-actin ring in S. pombe.

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Year:  1997        PMID： 9459302     DOI： 10.1016/s0014-5793(97)01510-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  29 in total

1.  Myosin-II tails confer unique functions in Schizosaccharomyces pombe: characterization of a novel myosin-II tail.

Authors:  M Bezanilla; T D Pollard
Journal:  Mol Biol Cell       Date:  2000-01       Impact factor: 4.138

2.  Drc1p/Cps1p, a 1,3-beta-glucan synthase subunit, is essential for division septum assembly in Schizosaccharomyces pombe.

Authors:  J Liu; H Wang; D McCollum; M K Balasubramanian
Journal:  Genetics       Date:  1999-11       Impact factor: 4.562

3.  Analysis of mid1p, a protein required for placement of the cell division site, reveals a link between the nucleus and the cell surface in fission yeast.

Authors:  A Paoletti; F Chang
Journal:  Mol Biol Cell       Date:  2000-08       Impact factor: 4.138

4.  Identification of two type V myosins in fission yeast, one of which functions in polarized cell growth and moves rapidly in the cell.

Authors:  F Motegi; R Arai; I Mabuchi
Journal:  Mol Biol Cell       Date:  2001-05       Impact factor: 4.138

5.  Genetic interaction between calcineurin and type 2 myosin and their involvement in the regulation of cytokinesis and chloride ion homeostasis in fission yeast.

Authors:  Masaaki Fujita; Reiko Sugiura; Yabin Lu; Linxiao Xu; Yujie Xia; Hisato Shuntoh; Takayoshi Kuno
Journal:  Genetics       Date:  2002-07       Impact factor: 4.562

6.  Cytokinesis depends on the motor domains of myosin-II in fission yeast but not in budding yeast.

Authors:  Matthew Lord; Ellen Laves; Thomas D Pollard
Journal:  Mol Biol Cell       Date:  2005-09-07       Impact factor: 4.138

7.  The Scw1 RNA-binding domain protein regulates septation and cell-wall structure in fission yeast.

Authors:  Jim Karagiannis; Rena Oulton; Paul G Young
Journal:  Genetics       Date:  2002-09       Impact factor: 4.562

8.  In vitro contraction of cytokinetic ring depends on myosin II but not on actin dynamics.

Authors:  Mithilesh Mishra; Jun Kashiwazaki; Tomoko Takagi; Ramanujam Srinivasan; Yinyi Huang; Mohan K Balasubramanian; Issei Mabuchi
Journal:  Nat Cell Biol       Date:  2013-06-16       Impact factor: 28.824

9.  Regulation of fission yeast myosin-II function and contractile ring dynamics by regulatory light-chain and heavy-chain phosphorylation.

Authors:  Thomas E Sladewski; Michael J Previs; Matthew Lord
Journal:  Mol Biol Cell       Date:  2009-07-01       Impact factor: 4.138

10.  Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation.

Authors:  Masayuki Onishi; Michihiro Iida; Takako Koga; Sadayuki Yamada; Aiko Hirata; Tomoko Iwaki; Kaoru Takegawa; Yasuhisa Fukui; Hiroyuki Tachikawa
Journal:  Eukaryot Cell       Date:  2007-10-19
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