Literature DB >> 94592

Placental alkaline phosphatase, alphafetoprotein and carcinoembryonic antigen in testicular tumors. Tissue typing by means of cytologic smears.

B Wahren, P A Holmgren, T Stigbrand.   

Abstract

Indirect immunofluorescence and radioimmunoassay with specific rabbit antisera demonstrated the occurrence of alphafetoprotein (AFP), carcinoembryonic antigen (CEA) and placental alkaline phosphatase (PLAP) in primary testicular tumor cells. Embryonal carcinomas had AFP- and CEA-containing cells, sometimes PLAP. PLAP and sometimes CEA were found in seminoma cells. Sera from patients with advanced non-seminomatous tumors could contain any of these antigens or any combination of them. Sera from patients with seminomas had raised PLAP or CEA. PLAP appears to be a new marker for seminoma.

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Year:  1979        PMID： 94592     DOI： 10.1002/ijc.2910240608

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  17 in total

1.  Pathobiology of intracranial germ-cell tumors: immunochemical, immunohistochemical, and electron microscopic investigations.

Authors:  H K Inoue; H Naganuma; N Ono
Journal:  J Neurooncol       Date:  1987       Impact factor: 4.130

2.  Advances in pathology and immunocytochemistry.

Authors:  E Heyderman
Journal:  J R Soc Med       Date:  1985       Impact factor: 5.344

3.  Profiles of epitope-defined markers in sera from patients with testicular germ cell tumors.

Authors:  H Yamamoto; U Rudén; P Esposti; K Hirano; T Stigbrand; L Andersson; H Hisazumi; B Wahren
Journal:  Urol Res       Date:  1988

4.  Carcinoembryonic antigen in germ cell tumours of the testis. An immunohistochemical study.

Authors:  J Matoska
Journal:  Histochem J       Date:  1984-04

Review 5.  Placental-like alkaline phosphatase in seminoma.

Authors:  K Koshida; B Wahren
Journal:  Urol Res       Date:  1990

6.  Heat-stable alkaline phosphatase as a marker for human and monkey type-I pneumocytes.

Authors:  E J Nouwen; N Buyssens; M E De Broe
Journal:  Cell Tissue Res       Date:  1990-05       Impact factor: 5.249

7.  Pst I restriction fragment length polymorphism of the human placental alkaline phosphatase gene in normal placentae and tumors.

Authors:  L Tsavaler; R C Penhallow; W Kam; H H Sussman
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

8.  Immunohistochemical localization of placental-like alkaline phosphatase in testis and germ-cell tumors using monoclonal antibodies.

Authors:  J Paiva; I Damjanov; P H Lange; H Harris
Journal:  Am J Pathol       Date:  1983-05       Impact factor: 4.307

9.  Regulation of the expression of alkaline phosphatase in a human breast-cancer cell line.

Authors:  T C Chang; J K Wang; M W Hung; C H Chiao; L C Tsai; G G Chang
Journal:  Biochem J       Date:  1994-10-01       Impact factor: 3.857

10.  Seminoma-derived Nagao isozyme is encoded by a germ-cell alkaline phosphatase gene.

Authors:  J L Millán; T Manes
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205
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