AIMS: The association between resting heart rate and changes in heart rate with all-cause, cardiovascular and cancer mortality was studied among 1827 men and 2929 women, aged 40-80 years, followed for 12 years. METHODS AND RESULTS: After adjustment for initial age, serum cholesterol, body mass index, systolic blood pressure, smoking and diabetes, the all-cause mortality hazard ratio was 1.7 (95% confidence interval 1.4-2.2) for heart rate increments of 20 beats.min-1 for men and 1.4 (confidence interval 1.1-1.8) for women. For cardiovascular mortality, the risk estimates were 1.7 (confidence interval 1.2-2.6) for men and 1.3 (confidence interval 0.9-2.0) for women. We observed no significant association between heart rate and cancer mortality. For women, stronger predictive information for all-cause mortality was provided if changes in heart rate were evident at the 2-year review. CONCLUSION: The resting heart rate is a predictor of mortality, independent of major cardiovascular risk factors.
AIMS: The association between resting heart rate and changes in heart rate with all-cause, cardiovascular and cancer mortality was studied among 1827 men and 2929 women, aged 40-80 years, followed for 12 years. METHODS AND RESULTS: After adjustment for initial age, serum cholesterol, body mass index, systolic blood pressure, smoking and diabetes, the all-cause mortality hazard ratio was 1.7 (95% confidence interval 1.4-2.2) for heart rate increments of 20 beats.min-1 for men and 1.4 (confidence interval 1.1-1.8) for women. For cardiovascular mortality, the risk estimates were 1.7 (confidence interval 1.2-2.6) for men and 1.3 (confidence interval 0.9-2.0) for women. We observed no significant association between heart rate and cancer mortality. For women, stronger predictive information for all-cause mortality was provided if changes in heart rate were evident at the 2-year review. CONCLUSION: The resting heart rate is a predictor of mortality, independent of major cardiovascular risk factors.
Authors: G S Hillis; M Woodward; A Rodgers; C K Chow; Q Li; S Zoungas; A Patel; R Webster; G D Batty; T Ninomiya; G Mancia; N R Poulter; J Chalmers Journal: Diabetologia Date: 2012-05 Impact factor: 10.122
Authors: Cecilia Castro-Diehl; Ana V Diez Roux; Susan Redline; Teresa Seeman; Paula McKinley; Richard Sloan; Steven Shea Journal: Sleep Date: 2016-11-01 Impact factor: 5.849