| Literature DB >> 9457762 |
M N Filimonova1, V P Gubskaya, I A Nuretdinov, M J Benedik, L M Bogomolnaya, M A Andreeva, I B Leshchinskaya.
Abstract
Structural and functional differences between isoforms Sm1 and Sm2, a lack of influence of free Mg2+ on the isoform structures, formation of DNA-magnesium complex serving with great probability as a real substrate for the nuclease has been summarized on the basis of experimental data. Mg2+ forming a complex with phosphate groups of DNA are supposed to further increase the electrophilicity of the phosphorus atoms besides causing a conformational change of the substrate.Entities:
Mesh：
Substances：
Year: 1997 PMID： 9457762
Source DB: PubMed Journal: Biochemistry (Mosc) ISSN： 0006-2979 Impact factor: 2.487