Literature DB >> 9457661

Effects of Ginkgo biloba extract (EGb 761) on learning and possible actions on aging.

C Cohen-Salmon1, P Venault, B Martin, M J Raffalli-Sébille, M Barkats, F Clostre, M C Pardon, Y Christen, G Chapouthier.   

Abstract

A study of the effect of Ginkgo biloba extract (EGb 761) has shown enhancing effects on training in adult and aged Swiss mice. An analysis of inbred mice has confirmed this sensitivity to EGb 761, but depending on the strains, with different effects at different ages. The most interesting results are related to improvements in performances observed with aged mice of the DBA/2J strain. The results obtained with inbred strains in the study of the mossy fibers of the hippocampus make it possible to suggest a link between the improvements in training and the histological structure of the hippocampus. This possibility, which can be confirmed by further studies, is presented here.

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Year:  1997        PMID： 9457661     DOI： 10.1016/s0928-4257(97)82409-6

Source DB:  PubMed          Journal:  J Physiol Paris        ISSN： 0928-4257


  9 in total

1.  The in vivo synaptic plasticity mechanism of EGb 761-induced enhancement of spatial learning and memory in aged rats.

Authors:  Yongfu Wang; Lei Wang; Jing Wu; Jingxia Cai
Journal:  Br J Pharmacol       Date:  2006-05       Impact factor: 8.739

2.  Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice.

Authors:  Yan Hou; Marwa A Aboukhatwa; De-Liang Lei; Kebreten Manaye; Ikhlas Khan; Yuan Luo
Journal:  Neuropharmacology       Date:  2009-11-14       Impact factor: 5.250

3.  The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms.

Authors:  Catarina Rendeiro; Jeremy P E Spencer; David Vauzour; Laurie T Butler; Judi A Ellis; Claire M Williams
Journal:  Genes Nutr       Date:  2009-09-02       Impact factor: 5.523

Review 4.  Polyphenols and human health: prevention of disease and mechanisms of action.

Authors:  David Vauzour; Ana Rodriguez-Mateos; Giulia Corona; Maria Jose Oruna-Concha; Jeremy P E Spencer
Journal:  Nutrients       Date:  2010-11-08       Impact factor: 5.717

5.  Effect of Ginkgo biloba special extract EGb 761® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers.

Authors:  G Zadoyan; D Rokitta; S Klement; A Dienel; R Hoerr; T Gramatté; U Fuhr
Journal:  Eur J Clin Pharmacol       Date:  2011-12-21       Impact factor: 2.953

Review 6.  Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects.

Authors:  David Vauzour
Journal:  Oxid Med Cell Longev       Date:  2012-06-03       Impact factor: 6.543

7.  Effects of Fruit and Vegetable-Based Nutraceutical on Cognitive Function in a Healthy Population: Placebo-Controlled, Double-Blind, and Randomized Clinical Trial.

Authors:  Juan Ángel Carrillo; Raúl Arcusa; María Pilar Zafrilla; Javier Marhuenda
Journal:  Antioxidants (Basel)       Date:  2021-01-15

8.  The neuroprotective potential of flavonoids: a multiplicity of effects.

Authors:  David Vauzour; Katerina Vafeiadou; Ana Rodriguez-Mateos; Catarina Rendeiro; Jeremy P E Spencer
Journal:  Genes Nutr       Date:  2008-12       Impact factor: 5.523

9.  Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor.

Authors:  Catarina Rendeiro; David Vauzour; Marcus Rattray; Pierre Waffo-Téguo; Jean Michel Mérillon; Laurie T Butler; Claire M Williams; Jeremy P E Spencer
Journal:  PLoS One       Date:  2013-05-28       Impact factor: 3.240
  9 in total

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