Literature DB >> 945717

Microbial models of mammalian metabolism: aromatic hydroxylation of isomeric xylenes.

R V Smith, D W Humphrey, K O Engel, J P Rosazza.   

Abstract

The ability of 11 microorganisms to convert o-, m-, and p-xylene to monophenolic metabolites was evaluated. Four organisms were found to produce qualitatively identical products to those observed with mammalian systems.

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Year:  1976        PMID： 945717      PMCID： PMC169796          DOI： 10.1128/aem.31.3.448-449.1976

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  6 in total

1.  Gas-liquid and thin-layer chromatographic determinations of xylenols in microbial extracts.

Authors:  R V Smith; J P Rosazza; K O Engel; D W Humphrey
Journal:  J Chromatogr       Date:  1975-03-19

2.  Microbial transformations of antitumor compounds. 1. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata.

Authors:  R E Betts; D E Walters; J P Rosazza
Journal:  J Med Chem       Date:  1974-06       Impact factor: 7.446

3.  Migration of deuterium during aryl hydroxylation. 3. Effect of ortho- and meta- substituents.

Authors:  J Daly; D Jerina
Journal:  Arch Biochem Biophys       Date:  1969-10       Impact factor: 4.013

4.  Hydroxylation of aromatic hydrocarbons in the rat.

Authors:  O M Bakke; R R Scheline
Journal:  Toxicol Appl Pharmacol       Date:  1970-05       Impact factor: 4.219

5.  Microbial models of mammalian metabolism. Aromatic hydroxylation.

Authors:  R V Smith; J P Rosazza
Journal:  Arch Biochem Biophys       Date:  1974-04-02       Impact factor: 4.013

6.  Arene oxides as intermediates in the oxidative metabolism of aromatic compounds. Isomerization of methyl-substituted arene oxides.

Authors:  N Kaubisch; J W Daly; D M Jerina
Journal:  Biochemistry       Date:  1972-08-01       Impact factor: 3.162
  6 in total
  2 in total

1.  Microbial models of mammalian metabolism: O-dealkylation of para-alkoxybiphenyls.

Authors:  R V Smith; S A Milton; P J Davis
Journal:  Appl Environ Microbiol       Date:  1982-07       Impact factor: 4.792

2.  Microbiological hydroxylation of estradiol: formation of 2- and 4-hydroxyestradiol by Aspergillus alliaceus.

Authors:  J Williamson; D Van Orden; J P Rosazza
Journal:  Appl Environ Microbiol       Date:  1985-03       Impact factor: 4.792
  2 in total

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