OBJECTIVE: This study aimed to better predict the early postoperative facial nerve (FN) function after acoustic neuroma (AN) resection. STUDY DESIGN: This study was a prospective series. SETTING: The surgery was conducted in a tertiary referral center. PATIENTS: A total of 44 patients undergoing AN resection with cranial nerve monitoring were observed for at least 1 year after surgery. MAIN OUTCOME MEASURES: The predictive value of amplitude of the FN stimulus response on the early postoperative FN function was measured. RESULTS: Cranial nerve monitoring in AN surgery was used to obtain the stimulation threshold and facial electromyograph response amplitudes to FN stimulation proximal and distal to the tumor at 0.2 V above threshold. Thirty-eight of forty-four patients studied had a low postresection threshold (< or = 0.1 V). Of these (10), 26% sustained a postoperative FN dysfunction of House-Brackmann (HB) grades 3-6. In an effort to improve the predictive value from cranial nerve monitoring, the response amplitude to suprathreshold stimulation was compared with the threshold and FN function. Eighty-nine percent of patients with an amplitude of > or =200 microV had a grade 1-2 early postoperative FN function, whereas only 41% of patients with < 200 microV had a grade 1-2 early postoperative FN function (p = 0.00035). Eighty-eight percent of patients with both a low threshold and high amplitude had a grade 1-2 early postoperative FN function, whereas the remaining 12% of patients had a grade 3-6 FN function (p = 0.0032). The false-positive rate of threshold alone in predicting a grade 1-2 FN function was 26% compared to 12% for low threshold and high amplitude combined. CONCLUSIONS: The use of FN threshold and amplitude together is superior to threshold alone as a predictor of early postoperative FN function.
OBJECTIVE: This study aimed to better predict the early postoperative facial nerve (FN) function after acoustic neuroma (AN) resection. STUDY DESIGN: This study was a prospective series. SETTING: The surgery was conducted in a tertiary referral center. PATIENTS: A total of 44 patients undergoing AN resection with cranial nerve monitoring were observed for at least 1 year after surgery. MAIN OUTCOME MEASURES: The predictive value of amplitude of the FN stimulus response on the early postoperative FN function was measured. RESULTS: Cranial nerve monitoring in AN surgery was used to obtain the stimulation threshold and facial electromyograph response amplitudes to FN stimulation proximal and distal to the tumor at 0.2 V above threshold. Thirty-eight of forty-four patients studied had a low postresection threshold (< or = 0.1 V). Of these (10), 26% sustained a postoperative FN dysfunction of House-Brackmann (HB) grades 3-6. In an effort to improve the predictive value from cranial nerve monitoring, the response amplitude to suprathreshold stimulation was compared with the threshold and FN function. Eighty-nine percent of patients with an amplitude of > or =200 microV had a grade 1-2 early postoperative FN function, whereas only 41% of patients with < 200 microV had a grade 1-2 early postoperative FN function (p = 0.00035). Eighty-eight percent of patients with both a low threshold and high amplitude had a grade 1-2 early postoperative FN function, whereas the remaining 12% of patients had a grade 3-6 FN function (p = 0.0032). The false-positive rate of threshold alone in predicting a grade 1-2 FN function was 26% compared to 12% for low threshold and high amplitude combined. CONCLUSIONS: The use of FN threshold and amplitude together is superior to threshold alone as a predictor of early postoperative FN function.
Authors: Jakob Unger; Christoph Hebisch; Jennifer E Phipps; João L Lagarto; Hanna Kim; Morgan A Darrow; Richard J Bold; Laura Marcu Journal: Biomed Opt Express Date: 2020-02-14 Impact factor: 3.732
Authors: Parthasarathy D Thirumala; Santhosh Kumar Mohanraj; Miguel Habeych; Kelley Wichman; Yue-Fang Chang; Paul Gardner; Carl Snyderman; Donald J Crammond; Jeffrey Balzer Journal: J Neurol Surg B Skull Base Date: 2012-05-25
Authors: David Calligaris; Diana Caragacianu; Xiaohui Liu; Isaiah Norton; Christopher J Thompson; Andrea L Richardson; Mehra Golshan; Michael L Easterling; Sandro Santagata; Deborah A Dillon; Ferenc A Jolesz; Nathalie Y R Agar Journal: Proc Natl Acad Sci U S A Date: 2014-09-22 Impact factor: 11.205