D J Eisenman1, S C Parisier. 1. Manhattan Eye, Ear and Throat Hospital, New York, New York 10021, USA.
Abstract
OBJECTIVE: This study aimed to determine whether chronic otitis media (COM) with cholesteatoma over time is associated with a decrease in neurosensory function. STUDY DESIGN: This study was a review of a database of all patients with cholesteatoma treated surgically. SETTING: The study was conducted at a tertiary care medical center and specialty hospital. PATIENTS: There were children and adults with unilateral COM with acquired, nontraumatic cholesteatoma in this study. INTERVENTIONS: All patients received preoperative pure-tone bone conduction and speech audiometry. MAIN OUTCOME MEASURES: Interaural difference between the cholesteatomatous and normal ears comparing bone conduction pure-tone average (BC-PTA), pure-tone threshold at 4,000 Hz (BC4000), and/or speech discrimination score (SDS) as measured by a repeated measures analysis of covariance, with age as a covariate was examined. RESULTS: A significant difference between ears for SDS and BC4000 that does not vary with age was identified. A significant interaural difference for the BC-PTA that varies with patient age was identified. CONCLUSIONS: Chronic otitis media with cholesteatoma is associated with a decrease in neurosensory function, even in the absence of frank inner ear invasion.
OBJECTIVE: This study aimed to determine whether chronic otitis media (COM) with cholesteatoma over time is associated with a decrease in neurosensory function. STUDY DESIGN: This study was a review of a database of all patients with cholesteatoma treated surgically. SETTING: The study was conducted at a tertiary care medical center and specialty hospital. PATIENTS: There were children and adults with unilateral COM with acquired, nontraumatic cholesteatoma in this study. INTERVENTIONS: All patients received preoperative pure-tone bone conduction and speech audiometry. MAIN OUTCOME MEASURES: Interaural difference between the cholesteatomatous and normal ears comparing bone conduction pure-tone average (BC-PTA), pure-tone threshold at 4,000 Hz (BC4000), and/or speech discrimination score (SDS) as measured by a repeated measures analysis of covariance, with age as a covariate was examined. RESULTS: A significant difference between ears for SDS and BC4000 that does not vary with age was identified. A significant interaural difference for the BC-PTA that varies with patient age was identified. CONCLUSIONS:Chronic otitis media with cholesteatoma is associated with a decrease in neurosensory function, even in the absence of frank inner ear invasion.
Authors: Rahul Mittal; Christopher V Lisi; Robert Gerring; Jeenu Mittal; Kalai Mathee; Giri Narasimhan; Rajeev K Azad; Qi Yao; M'hamed Grati; Denise Yan; Adrien A Eshraghi; Simon I Angeli; Fred F Telischi; Xue-Zhong Liu Journal: J Med Microbiol Date: 2015-08-05 Impact factor: 2.472