Literature DB >> 9455849

Origin of tripronucleate zygotes after intracytoplasmic sperm injection.

M Grossmann1, J M Calafell, N Brandy, J A Vanrell, C Rubio, A Pellicer, J Egozcue, F Vidal, J Santaló.   

Abstract

Zygotes morphologically classified as tripronuclear (3PN) after intracytoplasmic sperm injection (ICSI), which are thought to be digynic in their origin, were studied by fluorescent in-situ hybridization (FISH). FISH results allowed us to assess the suspected ploidy after morphological evaluation of the zygote and to determine the origin of the third pronuclei. Our results show that, firstly, 36% of those zygotes classified as 3PN following their morphological evaluation were, in fact, diploid, and secondly, the main cause for triploidy after ICSI is the non-extrusion of the second polar body.

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Year:  1997        PMID: 9455849     DOI: 10.1093/humrep/12.12.2762

Source DB:  PubMed          Journal:  Hum Reprod        ISSN: 0268-1161            Impact factor:   6.918


  12 in total

1.  Performing ICSI using an injection pipette with the smallest possible inner diameter and a long taper increases normal fertilization rate, decreases incidence of degeneration and tripronuclear zygotes, and enhances embryo development.

Authors:  Y Yavas; S Roberge; F Khamsi; P Shirazi; M W Endman; J C Wong
Journal:  J Assist Reprod Genet       Date:  2001-08       Impact factor: 3.412

2.  Estimation of second polar body retention rate after conventional insemination and intracytoplasmic sperm injection: in vitro observations from more than 5000 human oocytes.

Authors:  Richard Porter; Taer Han; Michael J Tucker; James Graham; Juergen Liebermann; E Scott Sills
Journal:  J Assist Reprod Genet       Date:  2003-09       Impact factor: 3.412

3.  The effect of human cumulus cells on the maturation and developmental potential of immature oocytes in ICSI cycles.

Authors:  Aijun Zhang; Bufang Xu; Yijuan Sun; Xiaowei Lu; Zhihong Niu; Qian Chen; Yun Feng; Chen Xu
Journal:  J Assist Reprod Genet       Date:  2012-02-22       Impact factor: 3.412

4.  Altered cleavage patterns in human tripronuclear embryos and their association to fertilization method: a time-lapse study.

Authors:  Mette Warming Joergensen; Inge Agerholm; Johnny Hindkjaer; Lars Bolund; Lone Sunde; Hans Jakob Ingerslev; Kirstine Kirkegaard
Journal:  J Assist Reprod Genet       Date:  2014-01-24       Impact factor: 3.412

5.  Diagnosis of abnormal human fertilization status based on pronuclear origin and/or centrosome number.

Authors:  Yoshiteru Kai; Kyoko Iwata; Yumiko Iba; Yasuyuki Mio
Journal:  J Assist Reprod Genet       Date:  2015-09-22       Impact factor: 3.412

6.  Pronuclear removal of tripronuclear zygotes can establish heteroparental normal karyotypic human embryonic stem cells.

Authors:  Hong-Qing Liao; Qi OuYang; Shuo-Ping Zhang; De-Hua Cheng; Guang-Xiu Lu; Ge Lin
Journal:  J Assist Reprod Genet       Date:  2016-01-04       Impact factor: 3.412

7.  Hydatidiform molar pregnancy following assisted reproduction.

Authors:  M Nickkho-Amiry; G Horne; M Akhtar; R Mathur; D R Brison
Journal:  J Assist Reprod Genet       Date:  2019-01-05       Impact factor: 3.412

8.  Recurrent triploidy due to a failure to complete maternal meiosis II: whole-exome sequencing reveals candidate variants.

Authors:  I Filges; I Manokhina; M S Peñaherrera; D E McFadden; K Louie; E Nosova; J M Friedman; W P Robinson
Journal:  Mol Hum Reprod       Date:  2014-12-11       Impact factor: 4.025

9.  Association of extended culture to blastocyst and pre-malignant gestational trophoblastic disease risk following IVF/ICSI-assisted reproduction cycles: an analysis of large UK national database.

Authors:  B G I K Bambaranda; R Bomiriya; P Mehlawat; M Choudhary
Journal:  J Assist Reprod Genet       Date:  2022-08-24       Impact factor: 3.357

10.  Evaluation of the developmental competence and chromosomal compliment of mouse oocytes derived from in-vitro growth and maturation of preantral follicles.

Authors:  Lihua Liu; Vincent W Aoki; Douglas T Carrell
Journal:  J Assist Reprod Genet       Date:  2008-02-06       Impact factor: 3.412

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