Literature DB >> 9454557

Genetic approaches to neuroethology.

M Heisenberg1.   

Abstract

In neuroethology, the nervous system and behavior are analyzed in the context of the animal's natural habitat and evolutionary history. For the last 30 years the influence of genetics on neuroethology has steadily grown, particularly in Drosophila. Genetic variants reveal new properties of neurons; they help to dissect neuronal circuits and complex behavioral systems; genetics provides new methods to visualize certain brain structures and to assign behavioural functions to them; and, finally, genetic variants can be used to test ecological models. While single-gene mutations can hve highly specific behavioral effects, molecular analysis of the corresponding genes reveals that the latter normally have a much broader functional scope. The 'graininess' of a functional model of the brain, therefore, is defined by the independent regulatory units of the genes rather than by the genes themselves.

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Year:  1997        PMID: 9454557     DOI: 10.1002/bies.950191205

Source DB:  PubMed          Journal:  Bioessays        ISSN: 0265-9247            Impact factor:   4.345


  6 in total

Review 1.  Behaviour genetics of Drosophila: non-sexual behaviour.

Authors:  Seema Sisodia; B N Singh
Journal:  J Genet       Date:  2005-08       Impact factor: 1.166

2.  Effects of mutations at the stambh A locus of Drosophila melanogaster.

Authors:  M Kumar; M Joseph; S Chandrashekaran
Journal:  J Genet       Date:  2001-08       Impact factor: 1.166

3.  The tamas gene, identified as a mutation that disrupts larval behavior in Drosophila melanogaster, codes for the mitochondrial DNA polymerase catalytic subunit (DNApol-gamma125).

Authors:  B Iyengar; J Roote; A R Campos
Journal:  Genetics       Date:  1999-12       Impact factor: 4.562

Review 4.  Drosophila melanogaster in the study of human neurodegeneration.

Authors:  Frank Hirth
Journal:  CNS Neurol Disord Drug Targets       Date:  2010-08       Impact factor: 4.388

5.  Sensory integration regulating male courtship behavior in Drosophila.

Authors:  Dimitrije Krstic; Werner Boll; Markus Noll
Journal:  PLoS One       Date:  2009-02-13       Impact factor: 3.240

6.  Novel memory mutants in Drosophila: behavioral characteristics of the mutant nemyP153.

Authors:  Nikolai G Kamyshev; Konstantin G Iliadi; Julia V Bragina; Elena A Kamysheva; Elena V Tokmatcheva; Thomas Preat; Elena V Savvateeva-Popova
Journal:  BMC Neurosci       Date:  2002-07-30       Impact factor: 3.288

  6 in total

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